Diabetic neuropathy is regarded as one of the most debilitating outcomes of diabetes
mellitus and may cause pain, decreased motility, and even amputation. Diabetic neuropathy …

Alzheimer's disease (AD) is the most common cause of dementia and one of the most
important causes of morbidity and mortality among the aging population. AD diagnosis is …

Diabetic encephalopathy, a severe complication of diabetes mellitus, is characterized by
neuroinflammation and aberrant synaptogenesis in the hippocampus leading to cognitive …

GSK3 has been implicated for years in the regulation of inflammation and addressed in a
plethora of scientific reports using a variety of experimental (disease) models and …

Accumulating studies suggest that overnutrition-associated obesity may lead to
development of type 2 diabetes mellitus and metabolic syndromes (MetS). MetS and its …

The advances in medicine, together with lifestyle modifications, led to a rising life
expectancy. Unfortunately, however, aging is accompanied by an alarming boost of age …

It has been well recognized that intake of diets rich in saturated fats could result in
development of metabolic disorders such as type 2 diabetes mellitus, obesity and …

Piperine, the major alkaloid constituent of black pepper, has been reported to possess a
wide range of pharmacological effects on the central nervous system, including …

The incidence of diabetes has more than doubled in the United States in the last 30 years
and the global disease rate is projected to double by 2030. Cognitive impairment has been …

The critical factor considered in a depression induced by diabetes is the inflammation
eliciting hippocampal, amygdala and thalamic neuronal injury. Therefore, inhibiting …