Ecology and genomics of Actinobacteria: new concepts for natural product discovery

DA van Bergeijk, BR Terlouw, MH Medema… - Nature Reviews …, 2020 - nature.com
Actinobacteria constitute a highly diverse bacterial phylum with an unrivalled metabolic
versatility. They produce most of the clinically used antibiotics and a plethora of other natural …

Growing a circular economy with fungal biotechnology: a white paper

V Meyer, EY Basenko, JP Benz, GH Braus… - Fungal biology and …, 2020 - Springer
Fungi have the ability to transform organic materials into a rich and diverse set of useful
products and provide distinct opportunities for tackling the urgent challenges before all …

Emergence of methicillin resistance predates the clinical use of antibiotics

J Larsen, CL Raisen, X Ba, NJ Sadgrove… - Nature, 2022 - nature.com
The discovery of antibiotics more than 80 years ago has led to considerable improvements
in human and animal health. Although antibiotic resistance in environmental bacteria is …

Plant and microbial strategies to improve the phosphorus efficiency of agriculture

AE Richardson, JP Lynch, PR Ryan, E Delhaize… - Plant and soil, 2011 - Springer
Background Agricultural production is often limited by low phosphorus (P) availability. In
developing countries, which have limited access to P fertiliser, there is a need to develop …

CRISPR/Cas9 Based Genome Editing of Penicillium chrysogenum

C Pohl, JAKW Kiel, AJM Driessen… - ACS Synthetic …, 2016 - ACS Publications
CRISPR/Cas9 based systems have emerged as versatile platforms for precision genome
editing in a wide range of organisms. Here we have developed powerful CRISPR/Cas9 tools …

[PDF][PDF] Enzymatic hydrolysis of cellulosic biomass

B Yang, Z Dai, SY Ding, CE Wyman - Biofuels, 2011 - academia.edu
Biological conversion of cellulosic biomass to fuels and chemicals offers the high yields to
products vital to economic success and the potential for very low costs. Enzymatic hydrolysis …

Fungal enzyme sets for plant polysaccharide degradation

J van den Brink, RP de Vries - Applied microbiology and biotechnology, 2011 - Springer
Enzymatic degradation of plant polysaccharides has many industrial applications, such as
within the paper, food, and feed industry and for sustainable production of fuels and …

Deciphering the Cryptic Genome: Genome-wide Analyses of the Rice Pathogen Fusarium fujikuroi Reveal Complex Regulation of Secondary Metabolism and Novel …

P Wiemann, CMK Sieber, KW Von Bargen… - PLoS …, 2013 - journals.plos.org
The fungus Fusarium fujikuroi causes “bakanae” disease of rice due to its ability to produce
gibberellins (GAs), but it is also known for producing harmful mycotoxins. However, the …

Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus

RP De Vries, R Riley, A Wiebenga, G Aguilar-Osorio… - Genome biology, 2017 - Springer
Abstract Background The fungal genus Aspergillus is of critical importance to humankind.
Species include those with industrial applications, important pathogens of humans, animals …

The RAVEN Toolbox and Its Use for Generating a Genome-scale Metabolic Model for Penicillium chrysogenum

R Agren, L Liu, S Shoaie, W Vongsangnak… - PLoS computational …, 2013 - journals.plos.org
We present the RAVEN (R econstruction, A nalysis and V isualization of M e tabolic N
etworks) Toolbox: a software suite that allows for semi-automated reconstruction of genome …