Nonribosomal peptides are products that fall into the class of secondary metabolites with a
diverse properties as toxins, siderophores, pigments, or antibiotics, among others. Unlike …

Streptomyces is one of the most versatile genera for biotechnological applications, widely
employed as platform in the production of drugs. Although streptomycetes have a complex …

In this study, we identified a suitable precursor and good cellular compartmentalization for
enhancing bioactive metabolites to produce biosynthetic zinc oxide nanoparticles (ZnO …

Secondary metabolites are produced at low titers by native producers due to tight
regulations of their productions in response to environmental conditions. Synthetic biology …

Concern over the reports of antibiotic‐resistant bacterial infections in hospitals and in the
community has been publicized in the media, accompanied by comments on the risk that we …

Avilamycin, an excellent growth-promoting feed additive, produced by Streptomyces
viridochromogenes, was widely used to promote the growth of poultry by inhibiting Gram …

Daptomycin produced by Streptomyces roseosporus is an important lipopeptide antibiotic
used to treat human infections caused by Gram-positive pathogenic bacteria, including drug …

Natural products have had a major impact upon quality of life, with antibiotics as a classic
example of having a transformative impact upon human health. In this contribution, we will …

The ratio of carbon to nitrogen (C/N) in media plays a crucial role in the production of
microbial carotenoids. However, the effects of a high C/N ratio on carotenoid production are …

16α-Hydroxyprednisolone, an anti-inflammatory drug, could be potentially obtained from
hydrocortisone bioconversion by combining a 1, 2-dehydrogenation reaction performed by …