Bladder cells are constantly exposed to multiple xenobiotics and bioactive metabolites. In
addition to this challenging chemical environment, they are also exposed to shear stress …

Progress in the understanding the receptor GPR39 is held up by inconsistent
pharmacological data. First, the endogenous ligand (s) remain (s) contentious. Data pointing …

Background and Aims Phagocytosis (efferocytosis) of apoptotic neutrophils by macrophages
anchors the resolution of intestinal inflammation. Efferocytosis prevents secondary necrosis …

Mass spectrometry-based omics technologies are increasingly used in perturbation studies
to map drug effects to biological pathways by identifying significant molecular events …

Pathogen inactivation techniques for blood products have been implemented to optimize
clinically safe blood components supply. The INTERCEPT system uses amotosalen together …

Background/aims Concerning healthcare approaches, a paradigm change from reactive
medicine to predictive approaches, targeted prevention, and personalisation of medical …

Background/aims Exposure to bioactive compounds from nutrition, pharmaceuticals,
environmental contaminants or other lifestyle habits may affect the human organism. To gain …

Aims Secondary, or functional, mitral regurgitation (FMR) was recently recognized as a
separate clinical entity, complicating heart failure with reduced ejection fraction (HFrEF) and …

Mass spectrometry-based omics technologies are of increasing relevance for drug
discovery. The identification of significant molecular events is a prerequisite in order to map …

Despite the increasing prevalence of patients with Long Covid Syndrome (LCS), to date the
pathophysiology of the disease is still unclear, and therefore diagnosis and therapy are a …