Whipworm and roundworm infections

KJ Else, J Keiser, CV Holland, RK Grencis… - Nature Reviews …, 2020 - nature.com
Trichuriasis and ascariasis are neglected tropical diseases caused by the gastrointestinal
dwelling nematodes Trichuris trichiura (a whipworm) and Ascaris lumbricoides (a …

Challenges and opportunities for control and elimination of soil-transmitted helminth infection beyond 2020

MC Freeman, O Akogun, V Belizario Jr… - PLoS neglected …, 2019 - journals.plos.org
More than half of the world's population lives in places endemic for soil-transmitted
helminths (STHs), and an estimated 1.45 billion people are infected [1, 2]. In 2017, the …

Soil-transmitted helminth infection, anemia, and malnutrition among preschool-age children in Nangapanda subdistrict, Indonesia

Y Djuardi, G Lazarus, D Stefanie… - PLoS neglected …, 2021 - journals.plos.org
Background Soil-transmitted helminth (STH) infections are still prevalent in Indonesia, with
roughly one-third of infected population being preschool-age children (PSC), which are …

Soil-transmitted helminth vaccines: are we getting closer?

A Zawawi, KJ Else - Frontiers in immunology, 2020 - frontiersin.org
Parasitic helminths infect over one-fourth of the human population resulting in significant
morbidity, and in some cases, death in endemic countries. Despite mass drug administration …

Molecular evidence of hybridization between pig and human Ascaris indicates an interbred species complex infecting humans

A Easton, S Gao, SP Lawton, S Bennuru, A Khan… - Elife, 2020 - elifesciences.org
Human ascariasis is a major neglected tropical disease caused by the nematode Ascaris
lumbricoides. We report a 296 megabase (Mb) reference-quality genome comprised of …

MALDI-TOF mass spectrometry as a diagnostic tool in human and veterinary helminthology: a systematic review

M Feucherolles, S Poppert, J Utzinger, SL Becker - Parasites & vectors, 2019 - Springer
Background Matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) mass
spectrometry (MS) has become a widely used technique for the rapid and accurate …

Essential oils as novel anthelmintic drug candidates

SK Panda, M Daemen, G Sahoo, W Luyten - Molecules, 2022 - mdpi.com
Helminths, with an estimated 1.5 billion annual global infections, are one of the major health
challenges worldwide. The current strategy of the World Health Organization to prevent …

Soil-transmitted helminthic vaccines: Where are we now?

MTJ Wong, NS Anuar, R Noordin, GJ Tye - Acta tropica, 2023 - Elsevier
It has been tested and proven that vaccination is still the best strategy to combat infectious
diseases. However, to date, there are still no vaccines against human soil-transmitted …

Disturbance in human gut microbiota networks by parasites and its implications in the incidence of depression

E Ramírez-Carrillo, O Gaona, J Nieto… - Scientific Reports, 2020 - nature.com
If you think you are in control of your behavior, think again. Evidence suggests that
behavioral modifications, as development and persistence of depression, maybe the …

Efficacy and Safety of Albendazole and High-Dose Ivermectin Coadministration in School-Aged Children Infected With Trichuris trichiura in Honduras: A Randomized …

G Matamoros, A Sánchez, JA Gabrie… - Clinical Infectious …, 2021 - academic.oup.com
Background The efficacy of currently available anthelminthics against Trichuris trichiura
infections is significatively lower than for other soil-transmitted helminths. The combination of …