Antimicrobial peptides: Their role as infection‐selective tracers for molecular imaging

T Ebenhan, O Gheysens, HG Kruger… - BioMed research …, 2014 - Wiley Online Library
Antimicrobial peptides (AMPs) are a heterogeneous class of compounds found in a variety
of organisms including humans and, so far, hundreds of these structures have been isolated …

Targeted imaging of bacterial infections: advances, hurdles and hopes

M van Oosten, M Hahn, LMA Crane… - FEMS microbiology …, 2015 - academic.oup.com
Bacterial infections represent an increasing problem in modern health care, in particular due
to ageing populations and accumulating bacterial resistance to antibiotics. Diagnosis is …

[HTML][HTML] Bone infection site targeting nanoparticle-antibiotics delivery vehicle to enhance treatment efficacy of orthopedic implant related infection

S Huo, X Qu, J Guo, X Liu, Q Hong, Y Wang, J Yang… - Bioactive Materials, 2022 - Elsevier
Orthopedic implants account for 99% of orthopedic surgeries, however, orthopedic implant-
related infection is one of the most serious complications owing to the potential for limb …

Optical imaging of bacterial infections

B Mills, M Bradley, K Dhaliwal - Clinical and translational imaging, 2016 - Springer
The rise in multidrug resistant (MDR) bacteria has become a global crisis. Rapid and
accurate diagnosis of infection will facilitate antibiotic stewardship and preserve our ability to …

Selectivity of antimicrobial peptides: a complex interplay of multiple equilibria

S Bobone, L Stella - Antimicrobial Peptides: Basics for Clinical Application, 2019 - Springer
Antimicrobial peptides (AMPs) attack bacterial membranes selectively, killing microbes at
concentrations that cause no toxicity to the host cells. This selectivity is not due to interaction …

Prospective of 68Ga Radionuclide Contribution to the Development of Imaging Agents for Infection and Inflammation

I Velikyan - Contrast Media & Molecular Imaging, 2018 - Wiley Online Library
During the last decade, the utilization of 68Ga for the development of imaging agents has
increased considerably with the leading position in the oncology. The imaging of infection …

Antimicrobial peptides as infection imaging agents: better than radiolabeled antibiotics

MS Akhtar, MB Imran, MA Nadeem… - International journal of …, 2012 - Wiley Online Library
Nuclear medicine imaging techniques offer whole body imaging for localization of number
and site of infective foci inspite of limitation of spatial resolution. The innate human immune …

Preclinical studies and prospective clinical applications for bacteria-targeted imaging: the future is bright

M Heuker, A Gomes, JM van Dijl, GM van Dam… - Clinical and translational …, 2016 - Springer
Bacterial infections are a frequently occurring and major complication in human healthcare,
in particular due to the rapid increase of antimicrobial resistance and the emergence of pan …

Molecular imaging in musculoskeletal infections with 99mTc-UBI 29-41 SPECT/CT

M Sathekge, O Garcia-Perez, D Paez, N El-Haj… - Annals of Nuclear …, 2018 - Springer
Objective To determine the added value of CT over planar and SPECT-only imaging in the
diagnosis of musculoskeletal infection using 99m Tc-UBI 29-4. Materials and methods 184 …

A pooled analysis of diagnostic value of 99mTc-ubiquicidin (UBI) scintigraphy in detection of an infectious process

A Ostovar, M Assadi, K Vahdat, I Nabipour… - Clinical nuclear …, 2013 - journals.lww.com
Purpose Although the data are promising from limited studies with technetium-99m
ubiquicidin (99m Tc-UBI) scintigraphy in detection of infection in humans, these studies have …