With the global prevalence of diabetes mellitus over recent decades, more patients suffered
from various diabetic complications, including diabetic ocular surface diseases that may …

Historically, the eye has been considered as an organ free of lymphatic vessels. In recent
years, however, it became evident, that lymphatic vessels or lymphatic-like vessels …

Objective Altered homeostasis of salivary gland (SG) epithelial cells in Sjögren's syndrome
(SS) could be the initiating factor that leads to inflammation, secretory dysfunction and …

Aim To introduce a novel dry eye mouse model induced by topical administration of the air
pollutant particulate matter 10 (PM 10). Method A total of 60 male BALB/c mice were used in …

Objective Salivary gland epithelial cells (SGECs) are key cellular drivers in the pathogenesis
of primary Sjögren's syndrome (SS); however, the mechanisms sustaining SGEC activation …

Purpose: The purpose of this study was to introduce a novel dry eye rat model induced by
aerosol exposure of particulate matter (PM). Methods: A total of 30 female Sprague Dawley …

Autophagy is a lysosomal pathway for the degradation of damaged proteins and intracellular
components that promotes cell survival under specific conditions. Apoptosis is, in contrast, a …

Corneal injury (CI) affects corneal integrity and transparency, deteriorating the patient's
quality of life. This study aimed to explore the molecular mechanisms by which exosomes …

Autophagy is known to be implicated in the pathogenesis of Sjögren syndrome (SS), but
evidences are limited. We aimed to examine the levels of autophagy markers in tear film and …

Dry eye and diabetic keratopathy represent the major diabetic complications in ocular
surface. Here we found that diabetic mice exhibited the early onset of reduced tear secretion …