Management of infants at risk for group B streptococcal disease

KM Puopolo, R Lynfield, JJ Cummings, I Hand… - …, 2019 - publications.aap.org
Group B streptococcal (GBS) infection remains the most common cause of neonatal early-
onset sepsis and a signiicant cause of late-onset sepsis among young infants …

Management of neonates born at≥ 35 0/7 weeks' gestation with suspected or proven early-onset bacterial sepsis

KM Puopolo, WE Benitz, TE Zaoutis, J Cummings… - …, 2018 - publications.aap.org
The incidence of neonatal early-onset sepsis (EOS) has declined substantially over the last
2 decades, primarily because of the implementation of evidence-based intrapartum …

Neonatal sepsis: a review of pathophysiology and current management strategies

MA Glaser, LM Hughes, A Jnah… - Advances in neonatal …, 2021 - journals.lww.com
Background: Early-onset sepsis, occurring within 72 hours of birth, and late-onset sepsis,
occurring after this time period, present serious risks for neonates. While culture-based …

Management of neonates born at≤ 34 6/7 weeks' gestation with suspected or proven early-onset bacterial sepsis

KM Puopolo, WE Benitz, TE Zaoutis, J Cummings… - …, 2018 - publications.aap.org
Early-onset sepsis (EOS) remains a serious and often fatal illness among infants born
preterm, particularly among newborn infants of the lowest gestational age. Currently, most …

Challenges in the diagnosis and management of neonatal sepsis

A Zea-Vera, TJ Ochoa - Journal of tropical pediatrics, 2015 - academic.oup.com
Neonatal sepsis is the third leading cause of neonatal mortality and a major public health
problem, especially in developing countries. Although recent medical advances have …

Neonatal infectious diseases: evaluation of neonatal sepsis

A Camacho-Gonzalez, PW Spearman… - Pediatric …, 2013 - pediatric.theclinics.com
Neonatal sepsis remains a feared and serious complication, especially among very low birth
weight (VLBW) preterm infants. Neonatal sepsis is divided into early-onset and late-onset …

Biomarkers for diagnosis of neonatal sepsis: a literature review

D Sharma, N Farahbakhsh, S Shastri… - The Journal of Maternal …, 2018 - Taylor & Francis
Sepsis is an important cause of mortality and morbidity in neonatal populations. There has
been constant search of an ideal sepsis biomarker that have high sensitivity, specificity …

Defining necrotizing enterocolitis: current difficulties and future opportunities

RM Patel, J Ferguson, SJ McElroy, M Khashu… - Pediatric …, 2020 - nature.com
Necrotizing enterocolitis (NEC) is a leading cause of morbidity and mortality in hospitalized
infants. First classified through Bell staging in 1978, a number of additional definitions of …

Neonatal sepsis: an old problem with new insights

BA Shah, JF Padbury - Virulence, 2014 - Taylor & Francis
Neonatal sepsis continues to be a common and significant health care burden, especially in
very-low-birth-weight infants (VLBW< 1500 g). Though intrapartum antibiotic prophylaxis has …

Culture-negative early-onset neonatal sepsis—at the crossroad between efficient sepsis care and antimicrobial stewardship

C Klingenberg, RF Kornelisse, G Buonocore… - Frontiers in …, 2018 - frontiersin.org
Sepsis is a leading cause of mortality and morbidity in neonates. Presenting clinical
symptoms are unspecific. Sensitivity and positive predictive value of biomarkers at onset of …