Computational modeling of cardiac hemodynamics: current status and future outlook
The proliferation of four-dimensional imaging technologies, increasing computational
speeds, improved simulation algorithms, and the widespread availability of powerful …
speeds, improved simulation algorithms, and the widespread availability of powerful …
[HTML][HTML] Heart blood flow simulation: a perspective review
Cardiovascular disease (CVD), the leading cause of death today, incorporates a wide range
of cardiovascular system malfunctions that affect heart functionality. It is believed that the …
of cardiovascular system malfunctions that affect heart functionality. It is believed that the …
Integrated heart—coupling multiscale and multiphysics models for the simulation of the cardiac function
Mathematical modeling of the human heart and its function can expand our understanding of
various cardiac diseases, which remain the most common cause of death in the developed …
various cardiac diseases, which remain the most common cause of death in the developed …
Amyloid‐β efflux from the central nervous system into the plasma
KF Roberts, DL Elbert, TP Kasten… - Annals of …, 2014 - Wiley Online Library
Objective The aim of this study was to measure the flux of amyloid‐β (Aβ) across the human
cerebral capillary bed to determine whether transport into the blood is a significant …
cerebral capillary bed to determine whether transport into the blood is a significant …
[HTML][HTML] Application of patient-specific computational fluid dynamics in coronary and intra-cardiac flow simulations: Challenges and opportunities
The emergence of new cardiac diagnostics and therapeutics of the heart has given rise to
the challenging field of virtual design and testing of technologies in a patient-specific …
the challenging field of virtual design and testing of technologies in a patient-specific …
lifex-cfd: An open-source computational fluid dynamics solver for cardiovascular applications
Computational fluid dynamics (CFD) is an important tool for the simulation of the
cardiovascular function and dysfunction. Due to the complexity of the anatomy, the …
cardiovascular function and dysfunction. Due to the complexity of the anatomy, the …
Impact of atrial fibrillation on left atrium haemodynamics: A computational fluid dynamics study
We analyse the haemodynamics of the left atrium, highlighting differences between healthy
individuals and patients affected by atrial fibrillation. The computational study is based on …
individuals and patients affected by atrial fibrillation. The computational study is based on …
[HTML][HTML] An electromechanics-driven fluid dynamics model for the simulation of the whole human heart
We introduce a multiphysics and geometric multiscale computational model, suitable to
describe the hemodynamics of the whole human heart, driven by a four-chamber …
describe the hemodynamics of the whole human heart, driven by a four-chamber …
A geometric multiscale model for the numerical simulation of blood flow in the human left heart
We present a new computational model for the numerical simulation of blood flow in the
human left heart. To this aim, we use the Navier-Stokes equations in an Arbitrary Lagrangian …
human left heart. To this aim, we use the Navier-Stokes equations in an Arbitrary Lagrangian …
Non‐Newtonian blood rheology impacts left atrial stasis in patient‐specific simulations
The lack of mechanically effective contraction of the left atrium (LA) during atrial fibrillation
(AF) disturbs blood flow, increasing the risk of thrombosis and ischemic stroke. Thrombosis …
(AF) disturbs blood flow, increasing the risk of thrombosis and ischemic stroke. Thrombosis …