Generation of neuronal diversity is a biological strategy widely used in the brain to process
complex information. The olfactory bulb is the first relay station of olfactory information in the …

The mammalian main olfactory bulb is a crucial processing centre for the sense of smell. The
olfactory bulb forms early during development and is functional from birth. However, the …

Spatial transcriptomic studies are becoming increasingly common and large, posing
important statistical and computational challenges for many analytic tasks. Here, we present …

The field of Deep Learning (DL) has seen a remarkable series of developments with
increasingly accurate and robust algorithms. However, the increase in performance has …

In most sensory modalities, neuronal connectivity reflects behaviorally relevant stimulus
features, such as spatial location, orientation, and sound frequency. By contrast, the …

The central processing pathways of the human olfactory system are not fully understood.
The olfactory bulb projects directly to a number of cortical brain structures, but the distinct …

Elucidating the neural circuits supporting odor identification remains an open challenge.
Here, we analyze the contribution of the two output cell types of the mouse olfactory bulb …

Synaptic inhibition critically influences sensory processing throughout the mammalian brain,
including the main olfactory bulb (MOB), the first station of sensory processing in the …

Odor landscapes contain complex blends of molecules that each activate unique,
overlapping populations of olfactory sensory neurons (OSNs). Despite the presence of …

Projection neurons (PNs) in the mammalian olfactory bulb (OB) receive input from the nose
and project to diverse cortical and subcortical areas. Morphological and physiological …