Stearoyl CoA desaturase-1: New insights into a central regulator of cancer metabolism
RA Igal - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2016 - Elsevier
The processes of cell proliferation, cell death and differentiation involve an intricate array of
biochemical and morphological changes that require a finely tuned modulation of metabolic …
biochemical and morphological changes that require a finely tuned modulation of metabolic …
Akt-ing up just about everywhere: compartment-specific Akt activation and function in receptor tyrosine kinase signaling
The serine/threonine kinase Akt is a master regulator of many diverse cellular functions,
including survival, growth, metabolism, migration, and differentiation. Receptor tyrosine …
including survival, growth, metabolism, migration, and differentiation. Receptor tyrosine …
Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules
Receptor tyrosine kinase (RTK)-mediated activation of downstream effector pathways such
as the RAS GTPase/MAP kinase (MAPK) signaling cascade is thought to occur exclusively …
as the RAS GTPase/MAP kinase (MAPK) signaling cascade is thought to occur exclusively …
[HTML][HTML] Combinatorial signal perception in the BMP pathway
The bone morphogenetic protein (BMP) signaling pathway comprises multiple ligands and
receptors that interact promiscuously with one another and typically appear in combinations …
receptors that interact promiscuously with one another and typically appear in combinations …
Integrins and cell metabolism: an intimate relationship impacting cancer
R Ata, CN Antonescu - International journal of molecular sciences, 2017 - mdpi.com
Integrins are important regulators of cell survival, proliferation, adhesion and migration.
Once activated, integrins establish a regulated link between the extracellular matrix and the …
Once activated, integrins establish a regulated link between the extracellular matrix and the …
Phase‐separated foci of EML4‐ALK facilitate signalling and depend upon an active kinase conformation
Variants of the oncogenic EML4‐ALK fusion protein contain a similar region of ALK
encompassing the kinase domain, but different portions of EML4. Here, we show that EML4 …
encompassing the kinase domain, but different portions of EML4. Here, we show that EML4 …
The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression
H Lazareth, C Henique, O Lenoir, VG Puelles… - Nature …, 2019 - nature.com
The mechanisms driving the development of extracapillary lesions in focal segmental
glomerulosclerosis (FSGS) and crescentic glomerulonephritis (CGN) remain poorly …
glomerulosclerosis (FSGS) and crescentic glomerulonephritis (CGN) remain poorly …
Fyn and TOM1L1 are recruited to clathrin-coated pits and regulate Akt signaling
R Cabral-Dias, S Lucarelli, K Zak, S Rahmani… - Journal of Cell …, 2022 - rupress.org
The epidermal growth factor (EGF) receptor (EGFR) controls many aspects of cell
physiology. EGF binding to EGFR elicits the membrane recruitment and activation of …
physiology. EGF binding to EGFR elicits the membrane recruitment and activation of …
Confinement of unliganded EGFR by tetraspanin nanodomains gates EGFR ligand binding and signaling
MG Sugiyama, AI Brown, J Vega-Lugo… - Nature …, 2023 - nature.com
The epidermal growth factor receptor (EGFR) is a central regulator of cell physiology. EGFR
is activated by ligand binding, triggering receptor dimerization, activation of kinase activity …
is activated by ligand binding, triggering receptor dimerization, activation of kinase activity …
Optimizing cathode materials for intermediate-temperature solid oxide fuel cells (SOFCs): Oxygen reduction on nanostructured lanthanum nickelate oxides
JSA Carneiro, RA Brocca, MLRS Lucena… - Applied Catalysis B …, 2017 - Elsevier
Kinetics of high temperature oxygen reduction reaction (ORR) on La 2 NiO 4+ δ (LNO)
nanostructures are investigated by means of electrochemical impedance spectroscopy, with …
nanostructures are investigated by means of electrochemical impedance spectroscopy, with …