Phenolic compounds: Current industrial applications, limitations and future challenges

BR Albuquerque, SA Heleno, MBPP Oliveira… - Food & function, 2021 - pubs.rsc.org
Phenolic compounds are natural bioactive molecules found mainly in plant tissues that have
shown interesting bioactivities, such as antioxidant, antimicrobial, anti-inflammatory, and …

Metabolic engineering of Escherichia coli for natural product biosynthesis

D Yang, SY Park, YS Park, H Eun, SY Lee - Trends in Biotechnology, 2020 - cell.com
Natural products are widely employed in our daily lives as food additives, pharmaceuticals,
nutraceuticals, and cosmetic ingredients, among others. However, their supply has often …

Kaempferol: A flavonoid with wider biological activities and its applications

SP Bangar, V Chaudhary, N Sharma… - Critical Reviews in …, 2023 - Taylor & Francis
Kaempferol and its derivatives are naturally occurring phytochemicals with promising
bioactivities. This flavonol can reduce the lipid oxidation in the human body, prevent the …

Escherichia coli as a host for metabolic engineering

S Pontrelli, TY Chiu, EI Lan, FYH Chen, P Chang… - Metabolic …, 2018 - Elsevier
Over the past century, Escherichia coli has become one of the best studied organisms on
earth. Features such as genetic tractability, favorable growth conditions, well characterized …

Design of stable and self-regulated microbial consortia for chemical synthesis

X Li, Z Zhou, W Li, Y Yan, X Shen, J Wang… - Nature …, 2022 - nature.com
Microbial coculture engineering has emerged as a promising strategy for biomanufacturing.
Stability and self-regulation pose a significant challenge for the generation of intrinsically …

Antimicrobial peptides (AMPs): roles, functions and mechanism of action

R Seyfi, FA Kahaki, T Ebrahimi… - International Journal of …, 2020 - Springer
Antimicrobial peptides (AMPs) are a crucial part of innate immunity that exist in the most of
living organisms. In fact, AMPs have ability to incite the innate immune response and combat …

Biosynthesis investigations of terpenoid, alkaloid, and flavonoid antimicrobial agents derived from medicinal plants

W Huang, Y Wang, W Tian, X Cui, P Tu, J Li, S Shi… - Antibiotics, 2022 - mdpi.com
The overuse of antibiotics in the past decades has led to the emergence of a large number
of drug-resistant microorganisms. In recent years, the infection rate caused by multidrug …

Pulsed electric field‐assisted extraction of valuable compounds from microorganisms

JM Martínez, C Delso, I Álvarez… - … Reviews in Food …, 2020 - Wiley Online Library
Microorganisms (bacteria, yeast, and microalgae) are a promising resource for products of
high value such as nutrients, pigments, and enzymes. The majority of these compounds of …

Modular co-culture engineering, a new approach for metabolic engineering

H Zhang, X Wang - Metabolic engineering, 2016 - Elsevier
With the development of metabolic engineering, employment of a selected microbial host for
accommodation of a designed biosynthetic pathway to produce a target compound has …

Engineering microbial consortia by division of labor

GW Roell, J Zha, RR Carr, MA Koffas, SS Fong… - Microbial cell …, 2019 - Springer
During microbial applications, metabolic burdens can lead to a significant drop in cell
performance. Novel synthetic biology tools or multi-step bioprocessing (eg, fermentation …