Axonal regeneration and formation of tripartite (axo-glial) junctions at damaged sites is a
prerequisite for early repair of injured spinal cord. Transplantation of stem cells at such sites …

Since the 1960s and the therapeutic use of hematopoietic stem cells of bone marrow origin,
there has been an increasing interest in the study of undifferentiated progenitors that have …

Stem cell has immense potential in regenerative cellular therapy. Mesenchymal stem cells
(MSCs) can become a potential attractive candidate for therapy due to its remarkable ability …

In the context of the role of multiple physical factors in dictating stem cell fate, the present
paper demonstrates the effectiveness of the intermittently delivered external electric field …

Ischemic stroke is the leading cause of mortality and long-term disability worldwide.
Disruption of the blood–brain barrier (BBB) is a prominent pathophysiological mechanism …

Mesenchymal stem cells have shown regenerative properties in many tissues. This feature
had originally been ascribed to their multipotency and thus their ability to differentiate into …

Introduction Stem cell-based therapies are considered to be a promising treatment method
for several clinical conditions such as Alzheimer's disease, Parkinson's disease, spinal cord …

Surface interactions at the biomaterial–cellular interface determine the proliferation and
differentiation of stem cells. Manipulating such interactions through the surface chemistry of …

A number of bioengineering strategies, using biophysical stimulation, are being explored to
guide the human mesenchymal stem cells (hMScs) into different lineages. In this context, we …

Background: MSCs are a promising therapeutic resource. Paracrine effects and the
induction of differentiation patterns are thought to represent the two primary mechanisms …