Emerging COVID-19 variants and their impact on SARS-CoV-2 diagnosis, therapeutics and vaccines

Q Fernandes, VP Inchakalody, M Merhi… - Annals of …, 2022 - Taylor & Francis
The emergence of novel and evolving variants of SARS-CoV-2 has fostered the need for
change in the form of newer and more adaptive diagnostic methods for the detection of …

Will SARS-CoV-2 variants of concern affect the promise of vaccines?

RK Gupta - Nature Reviews Immunology, 2021 - nature.com
Initial optimism regarding the development of COVID-19 vaccines has been tempered by the
emergence of new variants of SARS-CoV-2. Will vaccination be able to contain the …

Waning of BNT162b2 vaccine protection against SARS-CoV-2 infection in Qatar

H Chemaitelly, P Tang, MR Hasan… - … England Journal of …, 2021 - Mass Medical Soc
Background Waning of vaccine protection against severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection or coronavirus disease 2019 (Covid-19) is a concern …

mRNA-1273 COVID-19 vaccine effectiveness against the B. 1.1. 7 and B. 1.351 variants and severe COVID-19 disease in Qatar

H Chemaitelly, HM Yassine, FM Benslimane… - Nature medicine, 2021 - nature.com
The SARS-CoV-2 pandemic continues to be a global health concern. The mRNA-1273
(Moderna) vaccine was reported to have an efficacy of 94.1% at preventing symptomatic …

Effectiveness of an inactivated SARS-CoV-2 vaccine in Chile

A Jara, EA Undurraga, C González… - … England Journal of …, 2021 - Mass Medical Soc
Background Mass vaccination campaigns to prevent coronavirus disease 2019 (Covid-19)
are occurring in many countries; estimates of vaccine effectiveness are urgently needed to …

Effectiveness of the CoronaVac vaccine in older adults during a gamma variant associated epidemic of covid-19 in Brazil: test negative case-control study

OT Ranzani, MDT Hitchings, M Dorion, TL D'Agostini… - bmj, 2021 - bmj.com
Objective To estimate the effectiveness of the inactivated whole virus vaccine, CoronaVac
(Sinovac Biotech), against symptomatic covid-19 in the elderly population of São Paulo …

[PDF][PDF] COVID-19 weekly epidemiological update, edition 43, 8 June 2021

World Health Organization - 2021 - apps.who.int
Global case and death incidences continued to decrease with over 3 million new weekly
cases and over 73 000 new deaths, a 15% and an 8% decrease respectively, compared to …

SARS-CoV-2 (Covid-19) vaccines structure, mechanisms and effectiveness: A review

H Fathizadeh, S Afshar, MR Masoudi… - International Journal of …, 2021 - Elsevier
The world has been suffering from COVID-19 disease for more than a year, and it still has a
high mortality rate. In addition to the need to minimize transmission of the virus through non …

Estimating the early impact of vaccination against COVID-19 on deaths among elderly people in Brazil: Analyses of routinely-collected data on vaccine coverage and …

CG Victora, MC Castro, S Gurzenda, AC Medeiros… - …, 2021 - thelancet.com
Background: Vaccination against COVID-19 in Brazil started in January 2021, with health
workers and the elderly as the priority groups. We assessed whether there was an impact of …

[HTML][HTML] Clinical characteristics, transmissibility, pathogenicity, susceptible populations, and re-infectivity of prominent COVID-19 variants

Z Yang, S Zhang, YP Tang, S Zhang, DQ Xu… - Aging and …, 2022 - ncbi.nlm.nih.gov
In addition to the rapid, global spread of SARS-CoV-2, new and comparatively more
contagious variants are of considerable concern. These emerging mutations have become a …