Turning 21: induction of miR-21 as a key switch in the inflammatory response

FJ Sheedy - Frontiers in immunology, 2015 - frontiersin.org
miR-21 is one of the most highly expressed members of the small non-coding microRNA
family in many mammalian cell types. Its expression is further enhanced in many diseased …

MicroRNAs: history, biogenesis, and their evolving role in animal development and disease

M Bhaskaran, M Mohan - Veterinary pathology, 2014 - journals.sagepub.com
The discovery of microRNAs (miRNAs) in 1993 followed by developments and discoveries
in small RNA biology have redefined the biological landscape by significantly altering the …

MicroRNAs in development and disease

D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma

PP Medina, M Nolde, FJ Slack - Nature, 2010 - nature.com
MicroRNAs (miRNAs) belong to a recently discovered class of small RNA molecules that
regulate gene expression at the post-transcriptional level. miRNAs have crucial functions in …

MicroRNAs in NF-κB signaling

X Ma, LE Becker Buscaglia… - Journal of molecular cell …, 2011 - academic.oup.com
Nuclear factor κB (NF-κB) is a transcriptional factor that regulates a battery of genes that are
critical to innate and adaptive immunity, cell proliferation, inflammation, and tumor …

miR‐21: a small multi‐faceted RNA

AM Krichevsky, G Gabriely - Journal of cellular and molecular …, 2009 - Wiley Online Library
• miR‐21 expression in cancer and other diseases• Mechanisms of miR‐21 elevation in
cancer: multi‐level regulatory control• Transcriptional control• Post‐trancriptional regulation• …

MicroRNAs in breastmilk and the lactating breast: potential immunoprotectors and developmental regulators for the infant and the mother

M Alsaweed, PE Hartmann, DT Geddes… - International journal of …, 2015 - mdpi.com
Human milk (HM) is the optimal source of nutrition, protection and developmental
programming for infants. It is species-specific and consists of various bioactive components …

Coordinate regulation of FOXO1 by miR-27a, miR-96, and miR-182 in breast cancer cells

IK Guttilla, BA White - Journal of Biological Chemistry, 2009 - ASBMB
The FOXO1 transcription factor orchestrates the regulation of genes involved in the apoptotic
response, cell cycle checkpoints, and cellular metabolism. FOXO1 is a putative tumor …

[HTML][HTML] Immune-related microRNAs are abundant in breast milk exosomes

Q Zhou, M Li, X Wang, Q Li, T Wang, Q Zhu… - … journal of biological …, 2012 - ncbi.nlm.nih.gov
Breast milk is a complex liquid rich in immunological components that affect the
development of the infant's immune system. Exosomes are membranous vesicles of …

Molecular pathogenesis of Hodgkin's lymphoma: increasing evidence of the importance of the microenvironment

C Steidl, JM Connors, RD Gascoyne - Journal of Clinical Oncology, 2011 - ascopubs.org
Hodgkin's lymphoma (HL) represents the most common subtype of malignant lymphoma in
young people in the Western world. Most patients can be cured with modern treatment …