[HTML][HTML] Immune modulation after traumatic brain injury
Traumatic brain injury (TBI) induces instant activation of innate immunity in brain tissue,
followed by a systematization of the inflammatory response. The subsequent response …
followed by a systematization of the inflammatory response. The subsequent response …
[HTML][HTML] Staphylococcus aureus Host Tropism and Its Implications for Murine Infection Models
DM Mrochen, LM Fernandes de Oliveira… - International journal of …, 2020 - mdpi.com
Staphylococcus aureus (S. aureus) is a pathobiont of humans as well as a multitude of
animal species. The high prevalence of multi-resistant and more virulent strains of S. aureus …
animal species. The high prevalence of multi-resistant and more virulent strains of S. aureus …
[HTML][HTML] Regulatory T cells: angels or demons in the pathophysiology of sepsis?
Y Gao, Y Yao, X Zhang, F Chen, X Meng… - Frontiers in …, 2022 - frontiersin.org
Sepsis is a syndrome characterized by life-threatening organ dysfunction caused by the
dysregulated host response to an infection. Sepsis, especially septic shock and multiple …
dysregulated host response to an infection. Sepsis, especially septic shock and multiple …
[HTML][HTML] An immune-related gene signature predicts the 28-day mortality in patients with sepsis
Y Peng, Q Wu, H Liu, J Zhang, Q Han, F Yin… - Frontiers in …, 2023 - frontiersin.org
Introduction Sepsis is the leading cause of death in intensive care units and is characterized
by multiple organ failure, including dysfunction of the immune system. In the present study …
by multiple organ failure, including dysfunction of the immune system. In the present study …
[HTML][HTML] Prognostic significance of lymphocyte subpopulations for ICU-acquired infections in patients with sepsis: a retrospective study
J Zhao, RS Dai, YZ Chen, YG Zhuang - Journal of Hospital Infection, 2023 - Elsevier
Aim To determine the prognostic value of lymphocyte subpopulations in predicting intensive
care unit (ICU)-acquired infections among patients admitted to the ICU with sepsis. Methods …
care unit (ICU)-acquired infections among patients admitted to the ICU with sepsis. Methods …
Circulating regulatory T cells expressing tumor necrosis factor receptor type 2 contribute to sepsis-induced immunosuppression in patients during septic shock
BJ Gaborit, T Chaumette, M Chauveau… - The Journal of …, 2021 - academic.oup.com
Background Septic shock remains a major cause of death that can be complicated by long-
term impairment in immune function. Among regulatory T (Treg) cells, the tumor necrosis …
term impairment in immune function. Among regulatory T (Treg) cells, the tumor necrosis …
[HTML][HTML] Circulating LIGHT (TNFSF14) and interleukin-18 levels in sepsis-induced multi-organ injuries
The novel therapeutic target cytokine LIGHT (TNFSF14) was recently shown to play a major
role in COVID-19-induced acute respiratory distress syndrome (ARDS). This study aims to …
role in COVID-19-induced acute respiratory distress syndrome (ARDS). This study aims to …
Changes in immune function and immunomodulatory treatments of septic patients
Z Xu, A Liu, L Yang, B Zhang, F Zheng, J Zhang… - Clinical …, 2022 - Elsevier
Although the mortality rate of sepsis decreases annually, sepsis is still one of the most
common causes of death in hospitals. Specific treatments have not been researched yet …
common causes of death in hospitals. Specific treatments have not been researched yet …
[HTML][HTML] Staphylococcus aureus adaptive evolution: Recent insights on how immune evasion, immunometabolic subversion and host genetics impact vaccine …
T Wong Fok Lung, LC Chan, A Prince… - Frontiers in Cellular …, 2022 - frontiersin.org
Despite meritorious attempts, a S. aureus vaccine that prevents infection or mitigates
severity has not yet achieved efficacy endpoints in prospective, randomized clinical trials …
severity has not yet achieved efficacy endpoints in prospective, randomized clinical trials …
Decoding the potential role of regulatory T cells in sepsis‐induced immunosuppression
S Huang, D Liu, L Han, J Deng, Z Wang… - European Journal of …, 2024 - Wiley Online Library
Sepsis, a multiorgan dysfunction with high incidence and mortality, is caused by an
imbalanced host‐to‐infection immune response. Organ‐support therapy improves the early …
imbalanced host‐to‐infection immune response. Organ‐support therapy improves the early …