Nucleobase and nucleoside transport and integration into plant metabolism
C Girke, M Daumann, S Niopek-Witz… - Frontiers in plant …, 2014 - frontiersin.org
Nucleotide metabolism is an essential process in all living organisms. Besides newly
synthesized nucleotides, the recycling (salvage) of partially degraded nucleotides, ie …
synthesized nucleotides, the recycling (salvage) of partially degraded nucleotides, ie …
Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus
Abstract Background The fungal genus Aspergillus is of critical importance to humankind.
Species include those with industrial applications, important pathogens of humans, animals …
Species include those with industrial applications, important pathogens of humans, animals …
[HTML][HTML] Endocytosis of nutrient transporters in fungi: The ART of connecting signaling and trafficking
Plasma membrane transporters play pivotal roles in the import of nutrients, including sugars,
amino acids, nucleobases, carboxylic acids, and metal ions, that surround fungal cells. The …
amino acids, nucleobases, carboxylic acids, and metal ions, that surround fungal cells. The …
Origin, diversification and substrate specificity in the family of NCS 1/FUR transporters
NCS 1 proteins are H+/Na+ symporters specific for the uptake of purines, pyrimidines and
related metabolites. In this article, we study the origin, diversification and substrate specificity …
related metabolites. In this article, we study the origin, diversification and substrate specificity …
Molecular mechanism of ligand recognition by membrane transport protein, Mhp1
KJ Simmons, SM Jackson, F Brueckner… - The EMBO …, 2014 - embopress.org
The hydantoin transporter Mhp1 is a sodium‐coupled secondary active transport protein of
the nucleobase‐cation‐symport family and a member of the widespread 5‐helix inverted …
the nucleobase‐cation‐symport family and a member of the widespread 5‐helix inverted …
Function and regulation of fungal amino acid transporters: Insights from predicted structure
C Gournas, M Prévost, EM Krammer… - Yeast Membrane Transport, 2016 - Springer
Amino acids constitute a major nutritional source for probably all fungi. Studies of model
species such as the yeast Saccharomyces cerevisiae and the filamentous fungus …
species such as the yeast Saccharomyces cerevisiae and the filamentous fungus …
Uracil/H+ Symport by FurE Refines Aspects of the Rocking-bundle Mechanism of APC-type Transporters
Transporters mediate the uptake of solutes, metabolites and drugs across the cell
membrane. The eukaryotic FurE nucleobase/H+ symporter of Aspergillus nidulans has been …
membrane. The eukaryotic FurE nucleobase/H+ symporter of Aspergillus nidulans has been …
Mechanistic basis of pH-dependent 5-flucytosine resistance in Aspergillus fumigatus
F Gsaller, T Furukawa, PD Carr, B Rash… - Antimicrobial Agents …, 2018 - Am Soc Microbiol
ABSTRACT The antifungal drug 5-flucytosine (5FC), a derivative of the nucleobase cytosine,
is licensed for the treatment of fungal diseases; however, it is rarely used as a …
is licensed for the treatment of fungal diseases; however, it is rarely used as a …
The arrestin‐like protein ArtA is essential for ubiquitination and endocytosis of the UapA transporter in response to both broad‐range and specific signals
M Karachaliou, S Amillis, M Evangelinos… - Molecular …, 2013 - Wiley Online Library
We investigated the role of all arrestin‐like proteins of A spergillus nidulans in respect to
growth, morphology, sensitivity to drugs and specifically for the endocytosis and turnover of …
growth, morphology, sensitivity to drugs and specifically for the endocytosis and turnover of …
Dissection of transporter function: from genetics to structure
G Diallinas - Trends in Genetics, 2016 - cell.com
Transporters are transmembrane proteins mediating the selective uptake or efflux of solutes,
metabolites, drugs, or ions across cellular membranes. Despite their immense biological …
metabolites, drugs, or ions across cellular membranes. Despite their immense biological …