Mycobacterium tuberculosis is primarily a respiratory pathogen. However, 15% of infections
worldwide occur at extrapulmonary sites causing additional complications for diagnosis and …

Human immunodeficiency virus (HIV) and Mycobacterium tuberculosis (Mtb) are pathogens
responsible for millions of new infections each year; together, they cause high morbidity and …

Mycobacterium tuberculosis (Mtb) is the leading cause of death from infection worldwide.
The only available vaccine, BCG (Bacillus Calmette–Guérin), is given intradermally and has …

Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), is the most common cause of
death in people living with human immunodeficiency virus (HIV). Intra-dermal Bacille …

T cell immunity is essential for the control of tuberculosis (TB), an important disease of the
lung, and is generally studied in humans using peripheral blood cells. Mounting evidence …

Despite the success of antiretroviral therapy (ART), people living with HIV continue to suffer
from high burdens of respiratory infections, lung cancers and chronic lung disease at a …

Mycobacterium tuberculosis–specific (M. tuberculosis–specific) T cell responses associated
with immune control during asymptomatic latent tuberculosis infection (LTBI) remain poorly …

Despite widespread BCG vaccination and effective anti-TB drugs, Tuberculosis (TB) remains
the leading cause of death from an infectious agent worldwide. Several recent publications …

CD4+ T-cell depletion is pathognomonic for AIDS in both HIV and simian immunodeficiency
virus (SIV) infections. It occurs early, is massive at mucosal sites, and is not entirely reverted …

HIV/Mycobacterium tuberculosis (Mtb) co-infected individuals have an increased risk of
tuberculosis prior to loss of peripheral CD4 T cells, raising the possibility that HIV co …