The remarkable processes that characterize living organisms, such as motility, self-healing
and reproduction, are fuelled by a continuous injection of energy at the microscale. The field …

Infertility affects~ 7% of couples of reproductive age with little change in incidence in the last
two decades. ART, as well as other interventions, have made major strides in correcting this …

Living systems operate far from thermodynamic equilibrium. Enzymatic activity can induce
broken detailed balance at the molecular scale. This molecular scale breaking of detailed …

Living systems are complex dynamic entities that operate far from thermodynamic
equilibrium. Their active, non-equilibrium behaviour requires energy to drive cellular …

Actin plays roles in many important cellular processes, including cell motility, organelle
movement, and cell signaling. The discovery of transmembrane actin-binding proteins at the …

The mechanical properties of the cellular microenvironment and their spatiotemporal
variations are thought to play a central role in sculpting embryonic tissues, maintaining …

Particle tracking is a fundamental technique for investigating a variety of biophysical
processes, from intracellular dynamics to the characterization of cell motility and migration …

The invention of optical tweezers more than three decades ago has opened new avenues in
the study of the mechanical properties of biological molecules and cells. Quantitative force …

The healthy growth and maintenance of a biological system depends on the precise spatial
organization of molecules within the cell through the dissipation of energy. Reaction …

Fertilizable eggs develop from diploid precursor cells termed oocytes. Once every menstrual
cycle, an oocyte matures into a fertilizable egg in the ovary. To this end, the oocyte …