Newer Biologic and Small-Molecule Therapies for IBD There is still no cure for inflammatory
bowel disease. This review covers newer treatments that reflect our understanding of the …

Gut-associated lymphoid tissues (GALT) are the key antigen sampling and adaptive immune
inductive sites within the intestinal wall. Human GALT includes the multi-follicular Peyer's …

Inflammatory bowel diseases (IBDs) such as Crohn's disease and ulcerative colitis are
characterized by uncontrolled activation of intestinal immune cells in a genetically …

The current coronavirus pandemic is an ongoing global health crisis due to COVID-19,
caused by severe acute respiratory syndrome coronavirus 2. Although COVID-19 leads to …

The 2020 annual meeting for IOIBD was scheduled to occur in March, but was cancelled
owing to the emergence of COVID-19. Given how this disease might affect patients with IBD …

Immune cell trafficking is a complex and tightly regulated process that is indispensable for
the body's fight against pathogens. However, it is also increasingly acknowledged that …

Intestinal immune cell trafficking has been identified as a central event in the pathogenesis
of inflammatory bowel diseases (IBD). Intensive research on different aspects of the immune …

The intestinal lumen contains an abundance of bacteria, viruses and fungi alongside
ingested material that shape the chronically active intestinal immune system from early life to …

Gastroenterologists will be all too familiar with the difficult decisions that managing
inflammatory bowel disease often presents. How aggressively should I treat this patient? Do …

B cells are critical to immune homeostasis at mucosal surfaces including those of the
gastrointestinal tract. B cell-related abnormalities, comprising of a lympho-plasmacytic …