The cardiac conduction system (CCS) consists of distinctive components that initiate and
conduct the electrical impulse required for the coordinated contraction of the cardiac …

In 2014, an extensive review discussing the major steps of cardiac development focusing on
growth, formation of primary and chamber myocardium and the development of the cardiac …

Pericytes are widely believed to function as mesenchymal stem cells (MSCs), multipotent
tissue-resident progenitors with great potential for regenerative medicine. Cultured pericytes …

The sinoatrial node (SAN) is the primary pacemaker of the heart and controls heart rate
throughout life. Failure of SAN function due to congenital disease or aging results in slowing …

The heartbeat originates within the sinoatrial node (SAN), a small structure containing<
10,000 genuine pacemaker cells. If the SAN fails, the∼ 5 billion working cardiomyocytes …

Rationale: The cardiac conduction system (CCS) consists of distinct components including
the sinoatrial node, atrioventricular node, His bundle, bundle branches, and Purkinje fibers …

The inability of multipotent cardiovascular progenitor cells (CPCs) to undergo multiple
divisions in culture has precluded stable expansion of precursors of cardiomyocytes and …

Cardiac pacemaking generation and modulation rely on the coordinated activity of several
processes. Although a wealth of evidence indicates a relevant role of the If (“funny,” or …

Pacemaker and conduction system myocytes play crucial roles in initiating and regulating
the contraction of the cardiac chambers. Genetic defects, acquired diseases, and aging …

The myocardium of the heart is composed of multiple highly specialized myocardial
lineages, including those of the ventricular and atrial myocardium, and the specialized …