High-risk human papillomaviral oncogenes E6 and E7 target key cellular pathways to achieve oncogenesis
Infection with high-risk human papillomavirus (HPV) has been linked to several human
cancers, the most prominent of which is cervical cancer. The integration of the viral genome …
cancers, the most prominent of which is cervical cancer. The integration of the viral genome …
Head and neck cancer
Most head and neck cancers are squamous cell carcinomas that develop in the upper
aerodigestive epithelium after exposure to carcinogens such as tobacco and alcohol …
aerodigestive epithelium after exposure to carcinogens such as tobacco and alcohol …
Epigenetics of aging and disease: a brief overview
C Pagiatakis, E Musolino, R Gornati… - Aging clinical and …, 2021 - Springer
Aging is an important risk factor for several human diseases such as cancer, cardiovascular
disease and neurodegenerative disorders, resulting from a combination of genetic and …
disease and neurodegenerative disorders, resulting from a combination of genetic and …
Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression
SA Selamat, BS Chung, L Girard, W Zhang… - Genome …, 2012 - genome.cshlp.org
Lung cancer is the leading cause of cancer death worldwide, and adenocarcinoma is its
most common histological subtype. Clinical and molecular evidence indicates that lung …
most common histological subtype. Clinical and molecular evidence indicates that lung …
Eurogin Roadmap: comparative epidemiology of HPV infection and associated cancers of the head and neck and cervix
ML Gillison, X Castellsagué… - … journal of cancer, 2014 - Wiley Online Library
The EUROGIN 2012 roadmap is focused on the comparative epidemiology of human
papillomavirus (HPV) associated head and neck squamous cell cancers (HNSCC) and …
papillomavirus (HPV) associated head and neck squamous cell cancers (HNSCC) and …
RETRACTED ARTICLE: Molecular mechanisms in progression of HPV-associated cervical carcinogenesis
SM Gupta, J Mania-Pramanik - Journal of biomedical science, 2019 - Springer
Cervical cancer is the fourth most frequent cancer in women worldwide and a major cause of
mortality in developing countries. Persistent infection with high-risk human papillomavirus …
mortality in developing countries. Persistent infection with high-risk human papillomavirus …
Human papillomaviruses-associated cancers: an update of current knowledge
Human papillomaviruses (HPVs), which are small, double-stranded, circular DNA viruses
infecting human epithelial cells, are associated with various benign and malignant lesions of …
infecting human epithelial cells, are associated with various benign and malignant lesions of …
Genomic risk factors for cervical cancer
D Ramachandran, T Dörk - Cancers, 2021 - mdpi.com
Simple Summary Cervical cancer is the fourth leading cause of cancer-related deaths in
females worldwide. Despite an active immunisation strategy in many countries, high-risk …
females worldwide. Despite an active immunisation strategy in many countries, high-risk …
Epigenetic variability in cells of normal cytology is associated with the risk of future morphological transformation
AE Teschendorff, A Jones, H Fiegl, A Sargent… - Genome medicine, 2012 - Springer
Background Recently, it has been proposed that epigenetic variation may contribute to the
risk of complex genetic diseases like cancer. We aimed to demonstrate that epigenetic …
risk of complex genetic diseases like cancer. We aimed to demonstrate that epigenetic …
Clinical, morphologic and molecular heterogeneity of HPV-associated oropharyngeal cancer
The incidence of human papillomavirus-positive (HPV+) oropharyngeal squamous cell
carcinoma (OPSCC) is rising rapidly and has exceeded cervical cancer to become the most …
carcinoma (OPSCC) is rising rapidly and has exceeded cervical cancer to become the most …