It is well established that mutations in the canonical WNT-signalling pathway play a major
role in various cancers. Critical to developing new therapeutic strategies is understanding …

Ribosome biogenesis is a complex process that is responsible for the formation of
ribosomes and ultimately global protein synthesis. The first step in this process is the …

The nucleolus of a cell is a critical cellular compartment that is responsible for ribosome
biogenesis and plays a central role in tumor progression. Fisetin, a nutraceutical, is a …

Background Ribosomal biogenesis and ribosomal proteins have attracted attention in the
context of tumor biology in recent years. Instead of being mere translational machineries …

Abstract Lanthanum (La) and cerium (Ce), rare earth elements with physical properties
similar to calcium (Ca), are generally considered non-toxic when used appropriately …

Metastatic dissemination from the primary tumor is a complex process that requires crosstalk
between tumor cells and the surrounding milieu and involves the interplay between …

Tumor metastasis is still an insurmountable obstacle in tumor treatment. Lung cancer
represents one of the most common malignancies with high morbidity worldwide. hnRNPA1 …

Despite advances in treatment strategies, colorectal cancer (CRC) continues to cause
significant morbidity and mortality, with mounting evidence a close link between immune …

The nucleolus functions as a multi-layered regulatory hub for ribosomal RNA (rRNA)
biogenesis and ribosome assembly. Long noncoding RNAs (lncRNAs) in the nucleolus …

Never in mitosis gene A (NIMA)-related kinase-8 (NEK8) is involved in cell cycle
progression, cytoskeleton development, and DNA damage repair. However, its role in breast …