Cells are able to execute apoptosis by activating series of specific biochemical reactions.
One of the most prominent characteristics of cell death is the externalization of …

Blood glucose concentrations are maintained by insulin secreted from β-cells located in the
islets of Langerhans. There are∼ 2000 β-cells per islet, and∼ one million islets of …

Advanced imaging techniques have become a valuable tool in the study of complex
biological processes at the cellular level in biomedical research. Here, we introduce a new …

Aim To characterise changes in pancreatic beta cell mass during the development of
diabetes in untreated male C57BLKS/J db/db mice. Methods Blood samples were collected …

In this paper, we describe the synthesis and the photophysical properties of two novel near-
infrared (NIR) cyanine dyes (NIR5. 5-2 and NIR7. 0-2) which are water soluble potential …

Background Amyloidoses are characterized by the extracellular deposition of insoluble
fibrillar proteinaceous aggregates highly organized into cross-β structure and referred to as …

Macrophages play a dynamic role in tissue repair following injury. Here we found that
following streptozotocin (STZ)-induced beta-cell death, mouse islet macrophages had …

The widely used nonobese diabetic (NOD) mouse model of autoimmune (Type 1) diabetes
mellitus shares multiple characteristics with the human disease, and studies employing this …

The increasing incidence of diabetes requires a better understanding of the pathogenesis of
the clinical disease. Studies in prevention and treatment have been hampered by the single …

The development of new methods for noninvasive imaging is an area of biotechnology that
is of great relevance for the diagnosis and characterization of diabetes mellitus. Noninvasive …