The finding that chronic lymphocytic leukemia (CLL) consists of 2 clinical subsets,
distinguished by the incidence of somatic mutations in the immunoglobulin (Ig) variable …

Primary CNS lymphomas (PCNSL) represent malignant non-Hodgkin's B cell lymphomas,
which are confined to the central nervous system. They show a dramatic increase in …

In patients with active systemic lupus erythematosus (SLE), a marked B lymphocytopenia
was identified that affected CD19+/CD27− naive B cells more than CD19+/CD27+ memory B …

Clonal anergy is an enigmatic self-tolerance mechanism because no apparent purpose is
served by retaining functionally silenced B cells bearing autoantibodies. Human …

The study of human B cell tolerance has been hampered by difficulties in identifying a
sizable population of autoreactive B lymphocytes whose fate could be readily determined …

Ninety-four patients with infectious mononucleosis and symptoms⩽ 7 days were randomized
to treatment with oral acyclovir (800 mg 5 times/day) and prednisolone (0.7 mg/kg for the first …

Primary central nervous system lymphomas (PCNSLs) have recently received considerable
clinical attention due to their increasing incidence. To clarify the histogenetic origin of these …

Multiple sclerosis (MS) cerebrospinal fluid and brain contain increased IgG and oligoclonal
bands. Whether this oligoclonal and polyclonal IgG is directed against a disease‐relevant …

Abstract 9G4+ IgG Abs expand in systemic lupus erythematosus (SLE) in a disease-specific
fashion and react with different lupus Ags including B cell Ags and apoptotic cells. Their …

The classification of B cell tumors has relevance for refining and improving clinical
strategies. However, consensus has been difficult to establish, and although a scheme is …