The elucidation of the three dimensional structure of biological macromolecules has
provided an important contribution to our current understanding of many basic mechanisms …

Interactions of macromolecules with growing crystalline surfaces play an important role in
biomineralization, determine survival of some organisms at low temperatures, and offer a …

It is now just about 10 years since the publication of the first edition of Polymorphism in
Pharmaceutical Solids, which certainly received a positive reaction from workers in drug …

Serial femtosecond crystallography (SFX) has opened a new era in crystallography by
permitting nearly damage-free, room-temperature structure determination of challenging …

X-ray free-electron lasers (XFELs) provide very intense X-ray pulses suitable for
macromolecular crystallography. Each X-ray pulse typically lasts for tens of femtoseconds …

Accumulated experience during the last years on counterdiffusion crystallization methods
shows that they are a convenient and generally applicable way of optimizing solution crystal …

Counterdiffusion crystallization in capillary is a very simple, cost-effective, and practical
procedure for obtaining protein crystals suitable for X-ray data analysis. Its principles have …

Publisher Summary This chapter deals with the counterdiffusion methods for
macromolecular crystallization. The chapter gives a basic introduction to the use of the …

Capillary crystallization techniques and thermal microscopy have been used to identify and
characterize a metastable polymorph of metformin hydrochloride. The single crystal structure …

Spatial and temporal control of crystal nucleation is demonstrated by nonphotochemical
laser-induced nucleation of an aqueous agarose gel prepared with supersaturated …