Since the first clinical trials conducted after World War II, chemotherapeutic drugs have been
extensively used in the clinic as the main cancer treatment either alone or as an adjuvant …

It is extremely challenging to chemically diagnose disorders of the brain. There is hence
great interest in designing and optimizing tools for direct detection of chemical biomarkers …

Here, we synthesized and characterized graphene oxide (GO) fiber microelectrodes with
controllable nanosheet orientation to study the extent to which sheet alignment and …

Chemotherapy-induced cognitive impairment or chemobrain is a frequent consequence of
cancer treatment with many psychiatric features. Ironically, the increasing efficacy of …

In this work, we carried out neurochemical and behavioral analysis of zebrafish (Danio rerio)
treated with rotenone, an agent used to chemically induce a syndrome resembling …

There is an increased prevalence of cancer, and chemotherapy is widely and routinely
utilized to manage the majority of cancers; however, administration of chemotherapeutic …

Drosophila melanogaster, a fruit fly, is an exquisite model organism to understand
neurotransmission. Dopaminergic signaling in the Drosophila mushroom body (MB) is …

Alzheimer's disease (AD) is a progressive, fatal, neurodegenerative disorder for which only
treatments of limited efficacy are available. Despite early mentions of dementia in the …

The zebrafish is a powerful model organism to study the mechanisms governing transition
metal ions within whole brain tissue. Zinc is one of the most abundant metal ions in the …

Abstract Zinc (Zn (II)) is a divalent cation involved in regulating intracellular signal
transduction and gene expression through transcription factor activity, and can act as a …