Sex and gender in neurodevelopmental conditions

S Bölte, J Neufeld, PB Marschik, ZJ Williams… - Nature Reviews …, 2023 - nature.com
Health-related conditions often differ qualitatively or quantitatively between individuals of
different birth-assigned sexes and gender identities, and/or with different gendered …

[HTML][HTML] Chromosomal and environmental contributions to sex differences in the vulnerability to neurological and neuropsychiatric disorders: Implications for …

PN Pallier, M Ferrara, F Romagnolo, MT Ferretti… - Progress in …, 2022 - Elsevier
Neurological and neuropsychiatric disorders affect men and women differently. Multiple
sclerosis, Alzheimer's disease, anxiety disorders, depression, meningiomas and late-onset …

Carving the biodevelopment of same-sex sexual orientation at its joints

DP VanderLaan, MN Skorska, DE Peragine… - Gender and sexuality …, 2022 - Springer
Sexual orientation is a core aspect of human experience and understanding its development
is fundamental to psychology as a scientific discipline. Biological perspectives have played …

Deep learning models reveal replicable, generalizable, and behaviorally relevant sex differences in human functional brain organization

S Ryali, Y Zhang, C de Los Angeles… - Proceedings of the …, 2024 - National Acad Sciences
Sex plays a crucial role in human brain development, aging, and the manifestation of
psychiatric and neurological disorders. However, our understanding of sex differences in …

Gender and sex in eating disorders: A narrative review of the current state of knowledge, research gaps, and recommendations

É Breton, RP Juster, L Booij - Brain and behavior, 2023 - Wiley Online Library
Abstract Introduction Eating disorders (EDs) have long been considered conditions
exclusively affecting women, and studies in the ED field regularly exclude men. Research …

[HTML][HTML] Breaking the binary: gender versus sex analysis in human brain imaging

JM Rauch, L Eliot - Neuroimage, 2022 - Elsevier
Despite decades of pursuit, human brain imaging has yet to uncover clear neural correlates
of male-female behavioral differences. Given that such behavior does not always align with …

[HTML][HTML] Beyond “sex prediction”: Estimating and interpreting multivariate sex differences and similarities in the brain

C Sanchis-Segura, N Aguirre, ÁJ Cruz-Gómez, S Félix… - Neuroimage, 2022 - Elsevier
Previous studies have shown that machine-learning (ML) algorithms can “predict” sex based
on brain anatomical/functional features. The high classification accuracy achieved by ML …

Disconnectome of the migraine brain: a “connectopathy” model

M Silvestro, A Tessitore, G Caiazzo… - The Journal of …, 2021 - Springer
Background In the past decades a plethora of studies has been conducted to explore resting-
state functional connectivity (RS-FC) of the brain networks in migraine with conflicting results …

Beyond the binary: Characterizing the relationships between sex and neuropeptide receptor binding density measures in the rat brain

D Joel, CJ Smith, AH Veenema - Hormones and Behavior, 2024 - Elsevier
Sex differences exist in numerous parameters of the brain. Yet, sex-related factors are part of
a large set of variables that interact to affect many aspects of brain structure and function …

Novel isolation method reveals sex-specific composition and neurotoxicity of small extracellular vesicles in a mouse model of alzheimer's disease

A Elsherbini, Z Zhu, Z Quadri, SM Crivelli, X Ren… - Cells, 2023 - mdpi.com
We developed a new method to isolate small extracellular vesicles (sEVs) from male and
female wild-type and 5xFAD mouse brains to investigate the sex-specific functions of sEVs …