Activated by retinoids, metabolites of vitamin A, the retinoic acid receptors (RARs) and the
retinoid X receptors (RXRs) play important roles in a wide variety of biological processes …

Vitamin A is a fat-soluble vitamin important for vision, reproduction, embryonic development,
cell differentiation, epithelial barrier function and adequate immune responses. Efficient …

Antiretroviral drug therapy (ART) effectively suppresses replication of both the
immunodeficiency viruses, human (HIV) and simian (SIV); however, virus rebounds soon …

How developmental programs reactivate in regeneration is a fundamental question in
biology. We addressed this question through the study of Wound Induced Hair follicle …

Cadmium (Cd) is a ubiquitous toxic heavy metal of major public concern. Despite inefficient
placental transfer, maternal Cd exposure impairs fetal growth and development. Increasing …

Vitamin A deficiency has been shown to exacerbate allergic asthma. Previous studies have
postulated that retinoic acid (RA), an active metabolite of vitamin A and high-affinity ligand …

Hypothesis‐driven MS‐based targeted proteomics has gained great popularity in a relatively
short timespan. Next to the widely established selected reaction monitoring (SRM) workflow …

In mammals, all-trans retinoic acid (ATRA) is instrumental to spermatogenesis. It is
synthesized by two retinaldehyde dehydrogenases (RALDH) present in both Sertoli cells …

Vitamin A (VA), all-trans-retinol (ROL), and its analogs are collectively called retinoids.
Acting through the retinoic acid receptors RARα, RARβ, and RARγ, all-trans-retinoic acid, an …

Abstract Background Perivascular stromal cells (PSCs) are a recently identified cell type that
comprises a small percentage of the platelet derived growth factor receptor-β+ cells within …