COVID-19 2022 update: transition of the pandemic to the endemic phase

M Biancolella, VL Colona, R Mehrian-Shai, JL Watt… - Human genomics, 2022 - Springer
COVID-19, which is caused by the SARS-CoV-2, has ravaged the world for the past 2 years.
Here, we review the current state of research into the disease with focus on its history …

WWP1 E3 ligase at the crossroads of health and disease

A Behera, ABM Reddy - Cell Death & Disease, 2023 - nature.com
The E3 ubiquitin ligase WWP1 (WW Domain-containing E3 Ubiquitin Protein Ligase 1) is a
member of the HECT (Homologous to the E6-associated protein Carboxyl Terminus) E3 …

Syncytia formation during SARS-CoV-2 lung infection: a disastrous unity to eliminate lymphocytes

L Lin, Q Li, Y Wang, Y Shi - Cell Death & Differentiation, 2021 - nature.com
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection, has become a major threat to the global public health …

A focus on the spread of the delta variant of SARS-CoV-2 in India

G Novelli, VL Colona, PP Pandolfi - Indian Journal of Medical …, 2021 - journals.lww.com
538 INDIAN J MED RES, MAY & JUNE 2021 initial data show that this variant appears to
respond to currently available vaccines and is sensitive to antibodies generated by cured …

Thromboembolism after COVID-19 vaccine in patients with preexisting thrombocytopenia

A Mauriello, M Scimeca, I Amelio, R Massoud… - Cell death & …, 2021 - nature.com
While vaccination is the single most effective intervention to drastically reduce severe
disease and death following SARS-CoV-2 infection, as shown in UK and Israel, some …

Update on human genetic susceptibility to COVID-19: susceptibility to virus and response

VL Colona, V Vasiliou, J Watt, G Novelli… - Human genomics, 2021 - Springer
Update on human genetic susceptibility to COVID-19: susceptibility to virus and response |
Human Genomics Skip to main content SpringerLink Account Menu Find a journal Publish with …

Synthetic methodologies and therapeutic potential of indole-3-carbinol (I3C) and its derivatives

F Centofanti, A Buono, M Verboni, C Tomino… - Pharmaceuticals, 2023 - mdpi.com
Indole-3-carbinol (I3C) is a natural product contained in vegetables belonging to the
Brassicaceae family and has been studied in recent decades for its biological and …

Multiple E3 ligases act as antiviral factors against SARS-CoV-2 via inducing the ubiquitination and degradation of ORF9b

M Yu, J Li, W Gao, Z Li, W Zhang - Journal of Virology, 2024 - Am Soc Microbiol
Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) open reading frame 9b
(ORF9b) antagonizes the antiviral type I and III interferon (IFN) responses and is …

Indole-3-carbinol in vitro antiviral activity against SARS-Cov-2 virus and in vivo toxicity

F Centofanti, T Alonzi, A Latini, P Spitalieri… - Cell Death …, 2022 - nature.com
The effects of indole-3-carbinol (I3C) compound have been described deeply as antitumor
drug in multiple cancers. Herein, I3C compound was tested for toxicity and antiviral activity …

Elevated ubiquitination contributes to protective immunity against severe SARS‐CoV‐2 infection

Y Che, D Jiang, Y Zhang, J Zhang, T Xu… - Clinical and …, 2022 - Wiley Online Library
Background The crosstalk between the ubiquitin‐proteasome and the immune system plays
an important role in the health and pathogenesis of viral infection. However, there have …