Simple Summary Human epidermal growth factor receptors (HERs) are present in our body
and are responsible for regulating cell growth. When there is an overexpression of …

Background: Natural killer (NK) cells have potent effector functions that can be further
improved for therapeutic purposes through antibody-dependent cell-mediated cytotoxicity …

Synthetic biology seeks to enable the rational design of regulatory molecules and circuits to
reprogram cellular behavior. The application of this approach to human cells could lead to …

Ratiometric measurements utilizing two independent fluorescence signals from a dual-dye
molecular system help to improve the detection sensitivity and quantification of many …

Abstract Vitamin D3 (25-OH-D3) deficiency impairs rituximab-dependent cellular cytotoxicity
and the outcome of patients with diffuse large B-cell and follicular lymphomas (DLBCL) …

Acute lymphoblastic leukemia (ALL) represents around 25% of adult acute leukemias.
Despite the increasing improvement in the survival rate of ALL patients during the last …

Introduction: Advances in acute lymphocytic leukemia (ALL) therapy has led to long-term
survival rates in children. However, only 30%-40% of adults achieve long-term disease-free …

The ability of natural killer (NK) cells to kill tumor cells without antigen recognition makes
them appealing as an adoptive immunotherapy. However, NK cells are not routinely used in …

Pozadí problematiky: Adoptivní terapie pomocí T-buněk s chimerickými antigenními
receptory (CAR) specifickými na CD19 představuje slibnou léčbu relabujících nebo …

Background: The expression of HER2/neu in B-cell acute lymphoblastic leukemia has been
reported in previous studies. Objective: The objective of this research was to study the …