A continuous supply of oxygen is essential for the survival of multicellular organisms. The
understanding of how this supply is regulated in the microvasculature has evolved from …

Newborns, and especially those delivered preterm, are probably more prone to oxidative
stress than individuals later in life. Also during pregnancy, increased oxygen demand …

Infection with pathogenic influenza virus induces severe pulmonary immune pathology, but
the specific cell types that cause this have not been determined. We characterized …

Background Sepsis remains a common and serious condition with significant morbidity and
mortality due to multiple organ dysfunction, especially acute lung injury (ALI) and acute …

The role of oxidative stress has been well appreciated in the development of sepsis-induced
acute lung injury (ALI). Oxidative stress in sepsis-induced ALI is believed to be initiated by …

Recent studies suggest that exogenously administered CO is beneficial for the resolution of
acute inflammation. In this study, we assessed the role of CO liberated from a systemically …

抄録 Sepsis, as a severe systemic inflammatory response to bacterial infection, represents a
major clinical problem. It is characterized by the excessive production of reactive oxygen …

Increased endothelial permeability is central to the pathogenesis of sepsis and leads to
organ dysfunction and death but the endogenous mechanisms that drive increased …

Sepsis is a systemic inflammatory response that targets multiple components of the
cardiovascular system including the microvasculature. Microvascular endothelial cells …

Nitric oxide (NO) and hydrogen sulfide (H2S) are gasotransmitter molecules important in
numerous physiological and pathological processes. Although these molecules were first …