Essential hypertension is a common, complex disorder affecting≤ 1 billion adults globally.
Blood pressure is a highly heritable trait, with≤ 50% of the variation between individuals …

The exclusive expression of uromodulin in the kidneys has made it an intriguing protein in
kidney and cardiovascular research. Genome-wide association studies discovered variants …

Objectives To identify maternal plasma protein markers for early preeclampsia (delivery< 34
weeks of gestation) and to determine whether the prediction performance is affected by …

Urinary peptides gained significant attention as potential biomarkers especially in the
context of kidney and cardiovascular disease. In this manuscript the recent literature since …

Preeclampsia is a pregnancy-specific disorder that is a major cause of maternal and fetal
morbidity and mortality with a prevalence of 6–8% of pregnancies. Although impaired …

Hypertension is one of the most important and complex risk factors for cardiovascular
diseases (CVDs). By using urinary peptidomics analyses, we aimed to identify peptides …

Peptidomics is the comprehensive characterization of peptides from biological sources
mainly by HPLC and mass spectrometry. Mass spectrometry allows the detection of a …

Hypertension is a significant risk factor for cardiovascular disease and mortality worldwide.
The kidney is a major regulator of blood pressure and electrolyte homeostasis, with …

Preeclampsia (PE) is a condition that poses a significant risk of maternal mortality and
multiple organ failure during pregnancy. Early prediction of PE can enable timely …

Preeclampsia (PE) is a multisystem disorder associated with pregnancy and its frequency
varies from 5 to 20 percent of pregnancies. Although a number of preeclampsia studies have …