Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Recent progress in photosensitizers for overcoming the challenges of photodynamic therapy: from molecular design to application

X Zhao, J Liu, J Fan, H Chao, X Peng - Chemical Society Reviews, 2021 - pubs.rsc.org
Photodynamic therapy (PDT), a therapeutic mode involving light triggering, has been
recognized as an attractive oncotherapy treatment. However, nonnegligible challenges …

Visible-to-NIR-light activated release: from small molecules to nanomaterials

R Weinstain, T Slanina, D Kand, P Klan - Chemical reviews, 2020 - ACS Publications
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …

The unique features and promises of phthalocyanines as advanced photosensitisers for photodynamic therapy of cancer

PC Lo, MS Rodríguez-Morgade, RK Pandey… - Chemical Society …, 2020 - pubs.rsc.org
Phthalocyanines exhibit superior photoproperties that make them a surely attractive class of
photosensitisers for photodynamic therapy of cancer. Several derivatives are at various …

Photosensitizers for photodynamic therapy

M Lan, S Zhao, W Liu, CS Lee… - Advanced healthcare …, 2019 - Wiley Online Library
As an emerging clinical modality for cancer treatment, photodynamic therapy (PDT) takes
advantage of the cytotoxic activity of reactive oxygen species (ROS) that are generated by …

Theranostic fluorescent probes

A Sharma, P Verwilst, M Li, D Ma, N Singh… - Chemical …, 2024 - ACS Publications
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …

Phthalocyanines as medicinal photosensitizers: Developments in the last five years

X Li, BD Zheng, XH Peng, SZ Li, JW Ying… - Coordination Chemistry …, 2019 - Elsevier
Owing to their high extinction coefficients, long absorption wavelengths, and modification
tunable photophysical and photochemical properties, phthalocyanines (Pcs) have been …

Advanced photosensitizer activation strategies for smarter photodynamic therapy beacons

BM Luby, CD Walsh, G Zheng - … Chemie International Edition, 2019 - Wiley Online Library
Photodynamic therapy (PDT) is a clinical treatment in which a light‐absorbing drug called a
photosensitizer (PS) is combined with light and molecular oxygen to generate cytotoxic …

Stimulus-cleavable chemistry in the field of controlled drug delivery

Y Xue, H Bai, B Peng, B Fang, J Baell, L Li… - Chemical Society …, 2021 - pubs.rsc.org
Stimulus-cleavable nanoscale drug delivery systems are receiving significant attention
owing to their capability of achieving exquisite control over drug release via the exposure to …

Antitumor effect of photodynamic therapy/sonodynamic therapy/sono-photodynamic therapy of chlorin e6 and other applications

S Liao, M Cai, R Zhu, T Fu, Y Du, J Kong… - Molecular …, 2023 - ACS Publications
Chlorin e6 (Ce6) has been extensively researched and developed as an antitumor therapy.
Ce6 is a highly effective photosensitizer and sonosensitizer with promising future …