[HTML][HTML] mRNA vaccines: a new opportunity for malaria, tuberculosis and HIV

L Matarazzo, PJG Bettencourt - Frontiers in Immunology, 2023 - frontiersin.org
The success of the first licensed mRNA-based vaccines against COVID-19 has created a
widespread interest on mRNA technology for vaccinology. As expected, the number of …

[HTML][HTML] Next-Generation Vaccine Development with Nanomaterials: Recent Advances, Possibilities, and Challenges

S Shetty, PC Alvarado, D Pettie… - Annual Review of …, 2024 - annualreviews.org
Nanomaterials are becoming important tools for vaccine development owing to their tunable
and adaptable nature. Unique properties of nanomaterials afford opportunities to modulate …

[HTML][HTML] Tuberculosis vaccines update: Is an RNA-based vaccine feasible for tuberculosis?

SE Larsen, SL Baldwin, RN Coler - International Journal of Infectious …, 2023 - Elsevier
Abstract Objectives Despite concerted efforts, Mycobacterium tuberculosis (M. tb), the
pathogen that causes tuberculosis (TB), continues to be a burden on global health …

[HTML][HTML] Protective RNA nanovaccines against Mycobacterium avium subspecies hominissuis

BJB Touray, M Hanafy, Y Phanse… - Frontiers in …, 2023 - frontiersin.org
The induction of an effective immune response is critical for the success of mRNA-based
therapeutics. Here, we developed a nanoadjuvant system compromised of Quil-A and …

Sex differences in immune protection in mice conferred by heterologous vaccines for pneumonic plague

ML Davies, SS Biryukov, NO Rill, CP Klimko… - Frontiers in …, 2024 - frontiersin.org
Background Yersinia pestis is the etiological agent of plague, which can manifest as
bubonic, septicemic, and/or pneumonic disease. Plague is a severe and rapidly progressing …

[HTML][HTML] Enhancing TB Vaccine Efficacy: Current Progress on Vaccines, Adjuvants and Immunization Strategies

H Wang, S Wang, R Fang, X Li, J Xing, Z Li, N Song - Vaccines, 2023 - mdpi.com
Tuberculosis (TB) remains a global infectious disease primarily transmitted via respiratory
tract infection. Presently, vaccination stands as the primary method for TB prevention …

A Mrna Vaccine Induces Antimycobacterial Immunity by Activating DNA Damage Repair and Autophagy

D Chen, W Huang, L Shen, J Zhang, Z Pan, C Zhang… - papers.ssrn.com
Effective vaccines are urgently needed for the control of tuberculosis (TB). Here, we report
that a mRNA TB vaccine is highly effective and exhibits both prophylactic and therapeutic …