Current engineering and clinical aspects of needle-free injectors: A review

A Mohizin, JK Kim - Journal of Mechanical Science and Technology, 2018 - Springer
Needle-free injectors can be used to achieve non-invasive drug delivery by impregnating
biological barriers. They are considered as the future of drug delivery and therapeutic …

Advancements in transdermal drug delivery: A comprehensive review of physical penetration enhancement techniques

SS Gaikwad, AL Zanje, JD Somwanshi - International Journal of …, 2024 - Elsevier
Transdermal drug administration has grown in popularity in the pharmaceutical research
community due to its potential to improve drug bioavailability, compliance among patients …

Hydrodynamics of a dual-orifice needle-free jet injector

Y Rane, J Marston - Journal of Drug Delivery Science and Technology, 2024 - Elsevier
In the recent literature, it has been shown that an enhanced, multi-faceted, balanced
immune response can be generated using a combined intradermal (ID) and intramuscular …

In-vitro studies of jet injections

P Rohilla, JO Marston - International journal of pharmaceutics, 2019 - Elsevier
In this study, needle-free jet injection dynamics were studied using homogeneous gelatin as
model substrates. Whilst keeping nozzle properties such as orifice diameter (do) and …

Mechanism and clinical applications of needle‐free injectors in dermatology: literature review

HS Han, JY Hong, TR Kwon, SE Lee… - Journal of Cosmetic …, 2021 - Wiley Online Library
Background Needle‐free jet injectors are devices that deliver drugs using a high‐speed jet
without a needle. Recent studies have significantly increased our understanding of the …

Effect of geometrical parameters on the fluid dynamics of air-powered needle-free jet injectors

A Mohizin, JK Kim - Computers in Biology and Medicine, 2020 - Elsevier
Needle-free jet injectors are non-invasive systems having intradermal drug delivery
capabilities. At present, they revolutionize the next phase of drug delivery and therapeutic …

Impact of the mechanical properties of penetrated media on the injection characteristics of needle-free jet injection

A Mohizin, D Lee, JK Kim - Experimental Thermal and Fluid Science, 2021 - Elsevier
Needle-free jet injection systems are characterized by the increased drug delivery efficacy
over conventional needle-based injection systems and have become a viable alternative …

Dispersion profile of a needle-free jet injection depends on the interfacial property of the medium

A Mohizin, JK Kim - Drug Delivery and Translational Research, 2022 - Springer
Injections into or through the skin are common drug or vaccine administration routes, which
can be achieved with conventional needles, microneedles, or needle-free jet injections …

A scientometric analysis and visualization of scientific research and technology innovation in needle-free insulin injection from 1974 to 2022

Q Wang, Q Zhu, N Li - Clinical Therapeutics, 2023 - Elsevier
Purpose Needle-free jet injection has to some extent improved the quality of life of patients
with diabetes, but it has not been widely used. Therefore, we analyzed articles, clinical trials …

Effect of orientation angle for needle-free jet injection

I Lawal, DCA Valente, E Khusnatdinov, B Elliott… - International Journal of …, 2024 - Elsevier
In this paper, we report on the delivery efficiency of needle-free jet injections using injectors
with typical jet speed vj≈ 140 m/s, orifice diameter do= 157 μ m, and volume V= 0. 1 mL …