Topical drug delivery: History, percutaneous absorption, and product development
MS Roberts, HS Cheruvu, SE Mangion… - Advanced drug delivery …, 2021 - Elsevier
Topical products, widely used to manage skin conditions, have evolved from simple potions
to sophisticated delivery systems. Their development has been facilitated by advances in …
to sophisticated delivery systems. Their development has been facilitated by advances in …
Microneedle-based biosensing
Microneedles (MNs) are microscopic needles that are applied to the skin in a minimally
invasive way to facilitate transdermal drug delivery and/or uptake of interstitial fluid from the …
invasive way to facilitate transdermal drug delivery and/or uptake of interstitial fluid from the …
Microneedle patch for the ultrasensitive quantification of protein biomarkers in interstitial fluid
The detection and quantification of protein biomarkers in interstitial fluid is hampered by
challenges in its sampling and analysis. Here we report the use of a microneedle patch for …
challenges in its sampling and analysis. Here we report the use of a microneedle patch for …
Sampling interstitial fluid from human skin using a microneedle patch
PP Samant, MM Niedzwiecki, N Raviele… - Science translational …, 2020 - science.org
Tissue interstitial fluid (ISF) surrounds cells and is an underutilized source of biomarkers that
complements conventional sources such as blood and urine. However, ISF has received …
complements conventional sources such as blood and urine. However, ISF has received …
Mechanisms of sampling interstitial fluid from skin using a microneedle patch
PP Samant, MR Prausnitz - Proceedings of the National …, 2018 - National Acad Sciences
Although interstitial fluid (ISF) contains biomarkers of physiological significance and medical
interest, sampling of ISF for clinical applications has made limited impact due to a lack of …
interest, sampling of ISF for clinical applications has made limited impact due to a lack of …
Osmosis‐powered hydrogel microneedles for microliters of skin interstitial fluid extraction within minutes
Hydrogel microneedle patch enables the extraction of skin interstitial fluid (ISF) through in
situ swelling in a minimally invasive manner without assistance of mechano‐chemical …
situ swelling in a minimally invasive manner without assistance of mechano‐chemical …
Microneedle coupled epidermal sensor for multiplexed electrochemical detection of kidney disease biomarkers
Early diagnosis of chronic kidney disease (CKD) and constant monitoring to guide optimal
intervention is critical to prevent renal failure and other critical diseases. However, the …
intervention is critical to prevent renal failure and other critical diseases. However, the …
A silk-microneedle patch to detect glucose in the interstitial fluid of skin or plant tissue
Glucose is critical to all organisms. Herein, we developed a wire electrode embedded
microneedle patch (WEMNP) for in situ real-time detection of glucose in the interstitial fluid …
microneedle patch (WEMNP) for in situ real-time detection of glucose in the interstitial fluid …
[HTML][HTML] Design and fabrication of customizable microneedles enabled by 3D printing for biomedical applications
Microneedles (MNs) is an emerging technology that employs needles ranging from 10 to
1000 μm in height, as a minimally invasive technique for various procedures such as …
1000 μm in height, as a minimally invasive technique for various procedures such as …
Where microneedle meets biomarkers: futuristic application for diagnosing and monitoring localized external organ diseases
Extracellular tissue fluids are interesting biomatrices that have recently attracted scientists'
interest. Many significant biomarkers for localized external organ diseases have been …
interest. Many significant biomarkers for localized external organ diseases have been …