Botulinum neurotoxins: biology, pharmacology, and toxicology
M Pirazzini, O Rossetto, R Eleopra… - Pharmacological …, 2017 - ASPET
The study of botulinum neurotoxins (BoNT) is rapidly progressing in many aspects. Novel
BoNTs are being discovered owing to next generation sequencing, but their biologic and …
BoNTs are being discovered owing to next generation sequencing, but their biologic and …
[HTML][HTML] Mechanisms of botulinum toxin type A action on pain
Already a well-established treatment for different autonomic and movement disorders, the
use of botulinum toxin type A (BoNT/A) in pain conditions is now continuously expanding …
use of botulinum toxin type A (BoNT/A) in pain conditions is now continuously expanding …
[HTML][HTML] Botulinum toxin for the treatment of neuropathic pain
JH Park, HJ Park - Toxins, 2017 - mdpi.com
Botulinum toxin (BoNT) has been used as a treatment for excessive muscle stiffness,
spasticity, and dystonia. BoNT for approximately 40 years, and has recently been used to …
spasticity, and dystonia. BoNT for approximately 40 years, and has recently been used to …
[HTML][HTML] Toxicology and pharmacology of botulinum and tetanus neurotoxins: an update
Tetanus and botulinum neurotoxins cause the neuroparalytic syndromes of tetanus and
botulism, respectively, by delivering inside different types of neurons, metalloproteases …
botulism, respectively, by delivering inside different types of neurons, metalloproteases …
[HTML][HTML] Therapeutic efficacy and safety of Botulinum Toxin A Therapy in Trigeminal Neuralgia: a systematic review and meta-analysis of randomized controlled trials
Background Several different interventions have been examined to alleviate pain and
reduce frequency of trigeminal neuralgia (TN) paroxysms. However, some patients continue …
reduce frequency of trigeminal neuralgia (TN) paroxysms. However, some patients continue …
[HTML][HTML] Botulinum toxin for treating temporomandibular disorders: what is the evidence?
R Delcanho, M Val, LG Nardini… - … of oral & facial pain and …, 2022 - ncbi.nlm.nih.gov
Aims: To systematically review the scientific literature for evidence concerning the clinical
use of botulinum toxin (BTX) for the management of various temporomandibular disorders …
use of botulinum toxin (BTX) for the management of various temporomandibular disorders …
Botulinum toxin treatment of pain syndromes–an evidence based review
Y Safarpour, B Jabbari - Toxicon, 2018 - Elsevier
This review evaluates the existing level of evidence for efficacy of BoNTs in different pain
syndromes using the recommended efficacy criteria from the Assessment and Therapeutic …
syndromes using the recommended efficacy criteria from the Assessment and Therapeutic …
Botulinum toxin A, brain and pain
I Matak, Z Lacković - Progress in neurobiology, 2014 - Elsevier
Botulinum neurotoxin type A (BoNT/A) is one of the most potent toxins known and a potential
biological threat. At the same time, it is among the most widely used therapeutic proteins …
biological threat. At the same time, it is among the most widely used therapeutic proteins …
[HTML][HTML] The expanding therapeutic utility of botulinum neurotoxins
Botulinum neurotoxin (BoNT) is a major therapeutic agent that is licensed in neurological
indications, such as dystonia and spasticity. The BoNT family, which is produced in nature …
indications, such as dystonia and spasticity. The BoNT family, which is produced in nature …
Botulinum neurotoxin formulations: overcoming the confusion
S Samizadeh, K De Boulle - Clinical, cosmetic and investigational …, 2018 - Taylor & Francis
Botulinum toxin A is produced by anaerobic spore-forming bacteria and is used for various
therapeutic and cosmetic purposes. Botulinum toxin A injections are the most popular …
therapeutic and cosmetic purposes. Botulinum toxin A injections are the most popular …