As one of the problems and diseases for women before 40 years, premature ovarian failure
(POF) could be characterized by amenorrhea, low estrogen levels, infertility, high …

Premature ovarian insufficiency is a complex and relatively poorly understood entity with a
myriad of etiologies and multisystem sequelae that stem from premature deprivation of …

Premature ovarian failure (POF) causing hypergonadotrophic hypogonadism occurs in 1%
of women. In majority of cases the underlying cause is not identified. The known causes …

Recent elucidation of the role of central tolerance in preventing organ-specific autoimmunity
has changed our concepts of self/nonself discrimination. This paradigmatic shift is largely …

Organogenesis of the ovary is a highly orchestrated process involving multiple lineage
determination of ovarian surface epithelium, granulosa cells and theca cells. Although the …

Carcinoma in situ testis (CIS), also known as intratubular germ cell neoplasia (ITGCN), is a
pre-invasive precursor of testicular germ cell tumours, the commonest cancer type of male …

Androgens play pivotal roles in the regulation of male development and physiological
processes, particularly in the male reproductive system. Most biological effects of androgens …

One of the common disorders found in women is premature ovarian failure (POF). Recently
some studies have explained premature ovarian insufficiency (POI). The causes of it are …

Premature ovarian failure (POF) syndrome, an early decline of ovarian function in women, is
frequently associated with X chromosome abnormalities ranging from various Xq deletions …

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