Endometrial carcinoma is the most common gynecologic malignancy. A thorough
understanding of the epidemiology, pathophysiology, and management strategies for this …

Purpose To present evidence-based guidelines for adjuvant radiation in the treatment of
endometrial cancer. Methods and materials Key clinical questions to be addressed in this …

Background The PORTEC-3 trial investigated the benefit of combined adjuvant
chemotherapy and radiotherapy versus pelvic radiotherapy alone for women with high-risk …

Background Although women with endometrial cancer generally have a favourable
prognosis, those with high-risk disease features are at increased risk of recurrence. The …

Abstract The first joint European Society for Medical Oncology (ESMO), European SocieTy
for Radiotherapy & Oncology (ESTRO) and European Society of Gynaecological Oncology …

PURPOSE: To evaluate the very long-term results of the randomized Post Operative
Radiation Therapy in Endometrial Carcinoma (PORTEC)-1 trial for patients with Stage I …

Introduction: Endometrial cancer (EC) is the most common neoplasm of the female genital
tract in developed countries. Despite the progress in early detection and treatment, a …

Corpus cancer is surgically staged, therefore procedures previously used for determination
of stage are no longer applicable (eg the findings of fractional curettage to differentiate …

Background The role of frozen section (FS) in intraoperative decision making for surgical
staging of endometrial cancer is controversial. Objective of this study is to assess the …

OBJECTIVE: To determine if there is an advantage to combination chemotherapy and
radiation for optimally resected stage IIIC endometrial cancer (EC). METHODS: A multicenter …