Itch: from mechanism to (novel) therapeutic approaches
G Yosipovitch, JD Rosen, T Hashimoto - Journal of allergy and clinical …, 2018 - Elsevier
Itch is a common sensory experience that is prevalent in patients with inflammatory skin
diseases, as well as in those with systemic and neuropathic conditions. In patients with …
diseases, as well as in those with systemic and neuropathic conditions. In patients with …
[图书][B] In touch with the future: The sense of touch from cognitive neuroscience to virtual reality
Out of all the human senses, touch is the one that is most often unappreciated, and
undervalued. Yet, the surface of the human body, the skin, is actually one huge sheet of …
undervalued. Yet, the surface of the human body, the skin, is actually one huge sheet of …
Somatosensory pleasure circuit: from skin to brain and back
DM Lloyd, FP McGlone… - Experimental …, 2015 - Wiley Online Library
The skin senses serve a discriminative function, allowing us to manipulate objects and
detect touch and temperature, and an affective/emotional function, manifested as itch or pain …
detect touch and temperature, and an affective/emotional function, manifested as itch or pain …
[HTML][HTML] Central processing of itch in the midbrain reward center
Itch is an aversive sensation that evokes a desire to scratch. Paradoxically, scratching the
itch also produces a hedonic experience. The specific brain circuits processing these …
itch also produces a hedonic experience. The specific brain circuits processing these …
[HTML][HTML] Brain's reward circuits mediate itch relief. A functional MRI study of active scratching
ADP Papoiu, LA Nattkemper, KM Sanders, RA Kraft… - PLoS …, 2013 - journals.plos.org
Previous brain imaging studies investigating the brain processing of scratching used an
exogenous intervention mimicking scratching, performed not by the subjects themselves, but …
exogenous intervention mimicking scratching, performed not by the subjects themselves, but …
[HTML][HTML] Atopic dermatitis induces anxiety-and depressive-like behaviors with concomitant neuronal adaptations in brain reward circuits in mice
Clinically, it has been reported that atopic dermatitis (AD) has been linked with negative
emotional problems such as depression and anxiety, thereby reducing the quality of life, but …
emotional problems such as depression and anxiety, thereby reducing the quality of life, but …
[HTML][HTML] Acupuncture attenuates comorbid anxiety-and depressive-like behaviors of atopic dermatitis through modulating neuroadaptation in the brain reward circuit in …
M Yeom, S Ahn, SY Jang, JH Jang, Y Lee… - Biological …, 2022 - SciELO Chile
Atopic dermatitis (AD) is highly comorbid with negative emotions such as anxiety and
depression. Although acupuncture has demonstrated efficacy in AD, its influence on …
depression. Although acupuncture has demonstrated efficacy in AD, its influence on …
Can itch‐related visual stimuli alone provoke a scratch response in healthy individuals?
DM Lloyd, E Hall, S Hall… - British journal of …, 2013 - academic.oup.com
Background The sensation of itch and the scratch response elicited by application of
histamine are enhanced by itch‐related visual cues in people with existing skin conditions …
histamine are enhanced by itch‐related visual cues in people with existing skin conditions …
Central mechanisms of itch
H Mochizuki, R Kakigi - Clinical Neurophysiology, 2015 - Elsevier
Itch is a complex sensory and emotional experience. Functional brain imaging studies have
been performed to identify brain regions associated with this complex experience, and these …
been performed to identify brain regions associated with this complex experience, and these …
Addiction and the itch‐scratch cycle. What do they have in common?
Y Ishiuji - Experimental dermatology, 2019 - Wiley Online Library
Itch is a multidimensional experience involving various brain regions associated with
sensory perception and emotion, as well as an urge to scratch employing the motor system …
sensory perception and emotion, as well as an urge to scratch employing the motor system …