Antidepressant drugs are a standard biological treatment for various neuropsychiatric
disorders, yet relatively little is known about their electrophysiologic and synaptic effects on …

Due to the binding to a number of proteins to the receptor protomers in receptor heteromers
in the brain, the term “heteroreceptor complexes” was introduced. A number of serotonin 5 …

Studies on serotonin-selective reuptake inhibitors have established that disturbances in the
ascending 5-HT neuron systems and their 5-HT receptor subtypes and collateral networks to …

Higher risk of depression and schizophrenia in descendants of mothers experienced acute
infection during the pregnancy has been reported. Since monoamines are fundamental in …

Neuronal activity is altered in several neurological and psychiatric diseases. Upon
depolarization not only neurotransmitters are released but also cytokines and other …

Background: Wistar Kyoto (WKY) rats manifest abnormalities in the function of monoamine
receptors and transporters, as well as levels of these neurotransmitters in the brain. The …

Exposure by women to stressors before pregnancy increases their risk of contracting
prenatal depression, a condition which typically may require antidepressant treatment. And …

Background Bupropion is an aminoketone antidepressant. A major concern in bupropion
toxicity is seizure activity, which can occur up to 24 h from ingestion. It is difficult to predict …

Ketamine acts primarily by blocking the N-methyl-D-aspartate (NMDA) receptor at the
phencyclidine site. The rapid antidepressant properties of ketamine were demonstrated in …

Introduction Prenatal stress (PNS) and stress in adulthood are risk factors for development of
major depressive disorder. The present study aimed to 1) confirm previous neuroendocrine …