Nanoparticles in pregnancy: the next frontier in reproductive therapeutics
N Pritchard, T Kaitu'u-Lino, L Harris… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND Nanotechnology involves the engineering of structures on a molecular
level. Nanomedicine and nano-delivery systems have been designed to deliver therapeutic …
level. Nanomedicine and nano-delivery systems have been designed to deliver therapeutic …
Delivery technologies for women's health applications
The treatment of women's health-related conditions, including reproductive tract and
pregnancy disorders, faces distinct challenges and microenvironments, such as the vaginal …
pregnancy disorders, faces distinct challenges and microenvironments, such as the vaginal …
[HTML][HTML] Placenta-specific drug delivery by trophoblast-targeted nanoparticles in mice
Rationale: The availability of therapeutics to treat pregnancy complications is severely
lacking, mainly due to the risk of harm to the fetus. In placental malaria, Plasmodium …
lacking, mainly due to the risk of harm to the fetus. In placental malaria, Plasmodium …
Landscape of preterm birth therapeutics and a path forward
BS Coler, O Shynlova, A Boros-Rausch, S Lye… - Journal of Clinical …, 2021 - mdpi.com
Preterm birth (PTB) remains the leading cause of infant morbidity and mortality. Despite 50
years of research, therapeutic options are limited and many lack clear efficacy. Tocolytic …
years of research, therapeutic options are limited and many lack clear efficacy. Tocolytic …
Pharmacological interventions in labor and delivery
While there is not a wide range of pregnancy-specific drugs, there are some very specific
high-risk areas of obstetric care for which unique pharmacological approaches have been …
high-risk areas of obstetric care for which unique pharmacological approaches have been …
Surface-functionalized nanoparticles as efficient tools in targeted therapy of pregnancy complications
Minimizing exposure of the fetus to medication and reducing adverse off-target effects in the
mother are the primary challenges in developing novel drugs to treat pregnancy …
mother are the primary challenges in developing novel drugs to treat pregnancy …
Repurposing existing drugs as a therapeutic approach for the prevention of preterm birth
In brief Preterm birth is the leading cause of perinatal morbidity and mortality; however,
current therapies offer limited efficacy to delay birth and improve neonatal outcomes. This …
current therapies offer limited efficacy to delay birth and improve neonatal outcomes. This …
Diseases and conditions that impact maternal and fetal health and the potential for nanomedicine therapies
KM Nelson, MK Hoffman, JP Gleghorn… - Advanced drug delivery …, 2021 - Elsevier
Maternal mortality rates in the United States have steadily increased since 1987 to the
current rate of over 16 deaths per 100,000 live births. Whereas most of these deaths are …
current rate of over 16 deaths per 100,000 live births. Whereas most of these deaths are …
Safety and efficacy of tocolytics for the treatment of spontaneous preterm labour
RF Lamont, JS Jørgensen - Current pharmaceutical design, 2019 - ingentaconnect.com
Background: Preterm birth is the major cause of perinatal mortality and morbidity worldwide.
Attempts to reduce the burden may be proactive using biochemical or biophysical prediction …
Attempts to reduce the burden may be proactive using biochemical or biophysical prediction …
Nanotechnologies in obstetrics and cancer during pregnancy: a narrative review
S Bertozzi, B Corradetti, L Seriau… - Journal of Personalized …, 2022 - mdpi.com
Nanotechnology, the art of engineering structures on a molecular level, offers the
opportunity to implement new strategies for the diagnosis and management of pregnancy …
opportunity to implement new strategies for the diagnosis and management of pregnancy …