[HTML][HTML] Integrated analysis of whole blood oxylipin and cytokine responses after bacterial, viral, and T cell stimulation reveals new immune networks

E Villain, A Chanson, M Mainka, N Kampschulte… - Iscience, 2023 - cell.com
Oxylipins are major immunomodulating mediators, yet studies of inflammation focus mainly
on cytokines. Here, using a standardized whole-blood stimulation system, we characterized …

Leonurine ameliorates the inflammatory responses in lipopolysaccharide-induced endometritis

H Wu, A Dai, X Chen, X Yang, X Li, C Huang… - International …, 2018 - Elsevier
Endometritis is the inflammation of the endometrium that is associated with lower conception
rates, increased intervals from calving to first service, and more culls for failure to conceive …

[HTML][HTML] Involvement of TLR4 signaling regulated-COX2/PGE2 axis in liver fibrosis induced by Schistosoma japonicum infection

L Chen, X Ji, M Wang, X Liao, C Liang, J Tang, Z Wen… - Parasites & vectors, 2021 - Springer
Background Hepatic stellate cell (HSC) activation plays a pivotal role in hepatic
inflammation and liver fibrosis. TLR4 pathway activation has been reported to be involved in …

[HTML][HTML] DNA damage and apoptosis induced by a potent orally podophyllotoxin derivative in breast cancer

Y Wang, H Sun, Z Xiao, G Zhang, D Zhang… - Cell Communication and …, 2018 - Springer
Abstract Background Targeting TopoisomeraseII (TopoII) and generate enzyme mediated
DNA damage is an effective strategy for treatment of breast cancer. TopoII is known as a …

[HTML][HTML] The protective role of feruloylserotonin in LPS-induced HaCaT cells

Y He, B Kim, HE Kim, Q Sun, S Shi, G Ma, Y Kim, O Kim… - Molecules, 2019 - mdpi.com
Epidermal inflammation is caused by various bacterial infectious diseases that impair the
skin health. Feruloylserotonin (FS) belongs to the hydroxycinnamic acid amides of serotonin …

Role of Toll-like receptor 4/oxidant-coupled activation in regulating the biosynthesis of omega-3 polyunsaturated fatty acid derivative resolvin D1 in primary murine …

Y Zhang, OJ Igwe - Biochemical Pharmacology, 2018 - Elsevier
We have previously shown that reactive oxygen species (ROS) as prooxidants can activate
Toll-like receptor 4 (TLR4) with the potential to initiate, propagate and maintain “sterile” …

[HTML][HTML] Herbal melanin modulates PGE2 and IL-6 gastroprotective markers through COX-2 and TLR4 signaling in the gastric cancer cell line AGS

A El-Obeid, Y Maashi, R AlRoshody, G Alatar… - … Medicine and Therapies, 2023 - Springer
We reported a gastric anti-ulcerogenic effect of the Nigella sativa (L.)-derived herbal melanin
(HM) using rat models. However, the molecular mechanisms underlying this HM …

Antioxidants and/or fish oil reduce intermittent hypoxia-induced inflammation in the neonatal rat terminal ileum

G Mustafa, CL Cai, D Bodkin, JV Aranda… - Prostaglandins & Other …, 2021 - Elsevier
Intermittent hypoxia (IH) is associated with the pathogenesis of necrotizing enterocolitis
(NEC). We tested the hypothesis that early supplementation with antioxidants and/or fish oil …

[HTML][HTML] 百里香酚对脂多糖诱导的子宫内膜上皮细胞炎性反应的抑制作用研究

邵丹, 宋朋杰, 闫宝琪, 武小虎, 王东升, 李亚娟… - 畜牧兽医学报, 2019 - xml-data.org
为探究百里香酚治疗子宫内膜炎的抗炎活性, 利用脂多糖(LPS) 诱导山羊子宫内膜上皮细胞(
gEECs) 建立炎性模型, 以百里香酚进行干预. 采用NO 试剂盒和酶联免疫吸附试验(ELISA) …

[HTML][HTML] Changes in preoperative and postoperative lipoprotein-associated phospholipase A2 activity in patients with malignant obstructive jaundice

Y Zhao, G Feng, L Feng - Annals of Palliative Medicine, 2020 - apm.amegroups.org
Background: Malignant obstructive jaundice (MOJ) leads to hyperbilirubinemia and systemic
pathophysiological changes. The main clinical treatments for MOJ include radical …