The nicotinic acetylcholine receptor (nAChR) represents the prototype of ligand-gated ion
channels. It is vital for neuromuscular transmission and an important regulator of …

Neuropathic pain is a complex and debilitating syndrome for which there are few effective
pharmacological treatments. Opioid‐based medications are initially effective for acute pain …

The gut-brain axis describes a complex interplay between the central nervous system and
organs of the gastrointestinal tract. Sensory neurons of dorsal root and nodose ganglia …

Homomeric α7 nicotinic acetylcholine receptors (nAChRs) are abundantly expressed in the
central and peripheral nervous system (CNS and PNS, respectively), and spinal cord. In …

Prey shifts in carnivorous predators are events that can initiate the accelerated generation of
new biodiversity. However, it is seldom possible to reconstruct how the change in prey …

Nicotinic acetylcholine receptors (nAChRs) are essential for cellular communication in
higher organisms. Even though a vast pharmacological toolset to study cholinergic systems …

α6β4* nicotinic acetylcholine receptor (nAChR)(* represents the possible presence of
additional subunits) is mainly distributed in the central and peripheral nervous system and is …

Sensory neuron nicotinic acetylcholine receptors (nAChRs) contribute to pain associated
with tissue injury. However, there are marked differences between rats and mice with …

Background Parasympathetic innervation of meninges and ability of carbachol,
acetylcholine (ACh) receptor (AChR) agonist, to induce headaches suggests contribution of …

Change is intrinsic to nervous systems; change is required for learning and conditioning and
occurs with disease progression, normal development, and aging. To better understand …