Post-acute sequelae of COVID-19: understanding and addressing the burden of multisystem manifestations

M Parotto, M Gyöngyösi, K Howe, SN Myatra… - The Lancet …, 2023 - thelancet.com
Individuals with SARS-CoV-2 infection can develop symptoms that persist well beyond the
acute phase of COVID-19 or emerge after the acute phase, lasting for weeks or months after …

Respiratory sequelae of COVID-19: pulmonary and extrapulmonary origins, and approaches to clinical care and rehabilitation

SJ Singh, MM Baldwin, E Daynes, RA Evans… - The Lancet …, 2023 - thelancet.com
Although the exact prevalence of post-COVID-19 condition (also known as long COVID) is
unknown, more than a third of patients with COVID-19 develop symptoms that persist for …

Residual lung abnormalities after COVID-19 hospitalization: interim analysis of the UKILD post–COVID-19 study

I Stewart, J Jacob, PM George… - American journal of …, 2023 - atsjournals.org
Rationale: Shared symptoms and genetic architecture between coronavirus disease (COVID-
19) and lung fibrosis suggest severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Multi-organ impairment and long COVID: a 1-year prospective, longitudinal cohort study

A Dennis, DJ Cuthbertson, D Wootton… - Journal of the Royal …, 2023 - journals.sagepub.com
Objectives To determine the prevalence of organ impairment in long COVID patients at 6
and 12 months after initial symptoms and to explore links to clinical presentation. Design …

A persistent neutrophil-associated immune signature characterizes post–COVID-19 pulmonary sequelae

PM George, A Reed, SR Desai, A Devaraj… - Science translational …, 2022 - science.org
Interstitial lung disease and associated fibrosis occur in a proportion of individuals who have
recovered from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …

Post-acute sequelae of COVID-19 is characterized by diminished peripheral CD8+β7 integrin+ T cells and anti-SARS-CoV-2 IgA response

A Santa Cruz, A Mendes-Frias… - Nature …, 2023 - nature.com
Several millions of individuals are estimated to develop post-acute sequelae SARS-CoV-2
condition (PASC) that persists for months after infection. Here we evaluate the immune …

Pulmonary fibrosis: Emerging diagnostic and therapeutic strategies

B Selvarajah, M Platé, RC Chambers - Molecular Aspects of Medicine, 2023 - Elsevier
Fibrosis is the concluding pathological outcome and major cause of morbidity and mortality
in a number of common chronic inflammatory, immune-mediated and metabolic diseases …

Immune mechanisms in fibrotic interstitial lung disease

M Kamiya, H Carter, MS Espindola, TJ Doyle, JS Lee… - Cell, 2024 - cell.com
Fibrotic interstitial lung diseases (fILDs) have poor survival rates and lack effective therapies.
Despite evidence for immune mechanisms in lung fibrosis, immunotherapies have been …

Pulmonary function test and computed tomography features during follow-up after SARS, MERS and COVID-19: a systematic review and meta-analysis

CC Huntley, K Patel, F Mobeen… - ERJ open …, 2022 - Eur Respiratory Soc
Background The COVID-19 pandemic follows severe acute respiratory syndrome (SARS)
and Middle East respiratory syndrome (MERS) coronavirus epidemics. Some survivors of …

Parenchymal lung abnormalities following hospitalisation for COVID-19 and viral pneumonitis: a systematic review and meta-analysis

L Fabbri, S Moss, FA Khan, W Chi, J Xia, K Robinson… - Thorax, 2023 - thorax.bmj.com
Introduction Persisting respiratory symptoms in COVID-19 survivors may be related to
development of pulmonary fibrosis. We assessed the proportion of chest CT scans and …