Vitamin deficiencies in humans: can plant science help?

TB Fitzpatrick, GJC Basset, P Borel, F Carrari… - The Plant …, 2012 - academic.oup.com
The term vitamin describes a small group of organic compounds that are absolutely required
in the human diet. Although for the most part, dependency criteria are met in developed …

NO/cGMP-dependent modulation of synaptic transmission

R Feil, T Kleppisch - Pharmacology of neurotransmitter release, 2008 - Springer
Nitric oxide (NO) is a multifunctional messenger in the CNS that can signal both in antero-
and retrograde directions across synapses. Many effects of NO are mediated through its …

CD38 is critical for social behaviour by regulating oxytocin secretion

D Jin, HX Liu, H Hirai, T Torashima, T Nagai… - Nature, 2007 - nature.com
CD38, a transmembrane glycoprotein with ADP-ribosyl cyclase activity, catalyses the
formation of Ca2+ signalling molecules, but its role in the neuroendocrine system is …

CD38 and its role in oxytocin secretion and social behavior

H Higashida, S Yokoyama, M Kikuchi… - Hormones and Behavior, 2012 - Elsevier
Here, we review the functional roles of cyclic ADP-ribose and CD38, a transmembrane
protein with ADP-ribosyl cyclase activity, in mouse social behavior via the regulation of …

Factors and signals that govern the migration of dendritic cells via lymphatics: recent advances

GJ Randolph, G Sanchez-Schmitz, V Angeli - Springer seminars in …, 2005 - Springer
Dendritic cell (DC) migration from peripheral organs to lymph nodes plays a key role in
initiating immune responses, whether migratory DCs bring antigen in tow to lymph nodes or …

Proteomic analysis of pharmacological preconditioning: novel protein targets converge to mitochondrial metabolism pathways

DK Arrell, ST Elliott, LA Kane, Y Guo, YH Ko… - Circulation …, 2006 - Am Heart Assoc
Ischemic preconditioning is characterized by resistance to ischemia reperfusion injury in
response to previous short ischemic episodes, a protective effect that can be mimicked …

Social memory, amnesia, and autism: brain oxytocin secretion is regulated by NAD+ metabolites and single nucleotide polymorphisms of CD38

H Higashida, S Yokoyama, JJ Huang, L Liu… - Neurochemistry …, 2012 - Elsevier
Previously, we demonstrated that CD38, a transmembrane protein with ADP-ribosyl cyclase
activity, plays a critical role in mouse social behavior by regulating the release of oxytocin …

Cyclic ADP-ribose as a universal calcium signal molecule in the nervous system

H Higashida, AB Salmina, RY Olovyannikova… - Neurochemistry …, 2007 - Elsevier
β-NAD+ is as abundant as ATP in neuronal cells. β-NAD+ functions not only as a coenzyme
but also as a substrate. β-NAD+-utilizing enzymes are involved in signal transduction. We …

Neuron-glia interactions as therapeutic targets in neurodegeneration

AB Salmina - Journal of Alzheimer's Disease, 2009 - content.iospress.com
Accumulating evidence suggests that alterations of neuron-glia interactions are associated
with development of neurodegenerative diseases referred to as taupathies. Astrocytes …

Multiplicity of Ca2+ messengers and Ca2+ stores: a perspective from cyclic ADP-ribose and NAADP

HC Lee - Current molecular medicine, 2004 - ingentaconnect.com
It is generally believed that multiple Ca2+ stores are present in cells, a notion that has now
been made substantive by the discovery of multiple Ca2+ mobilizing messengers. Cyclic …