Clinical measures of bulbar dysfunction in ALS

Y Yunusova, EK Plowman, JR Green, C Barnett… - Frontiers in …, 2019 - frontiersin.org
Bulbar impairment represents a hallmark feature of Amyotrophic Lateral Sclerosis (ALS) that
significantly impacts survival and quality of life. Speech and swallowing dysfunction are key …

A systematic review and narrative analysis of digital speech biomarkers in Motor Neuron Disease

M Bowden, E Beswick, J Tam, D Perry, A Smith… - NPJ digital …, 2023 - nature.com
Abstract Motor Neuron Disease (MND) is a progressive and largely fatal neurodegeneritve
disorder with a lifetime risk of approximately 1 in 300. At diagnosis, up to 25% of people with …

Privacy implications of voice and speech analysis–information disclosure by inference

JL Kröger, OHM Lutz, P Raschke - … Management. Data for Better Living: AI …, 2020 - Springer
Internet-connected devices, such as smartphones, smartwatches, and laptops, have become
ubiquitous in modern life, reaching ever deeper into our private spheres. Among the sensors …

[HTML][HTML] Multimodal speech biomarkers for remote monitoring of ALS disease progression

M Neumann, H Kothare, V Ramanarayanan - Computers in Biology and …, 2024 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that
severely impacts affected persons' speech and motor functions, yet early detection and …

[HTML][HTML] Classification of ALS patients based on acoustic analysis of sustained vowel phonations

M Vashkevich, Y Rushkevich - Biomedical Signal Processing and Control, 2021 - Elsevier
Amyotrophic lateral sclerosis (ALS) is incurable neurological disorder with rapidly
progressive course. Common early symptoms of ALS are difficulty in swallowing and …

Repeatability of commonly used speech and language features for clinical applications

GM Stegmann, S Hahn, J Liss, J Shefner… - Digital …, 2020 - karger.com
Introduction: Changes in speech have the potential to provide important information on the
diagnosis and progression of various neurological diseases. Many researchers have relied …

Investigating the utility of multimodal conversational technology and audiovisual analytic measures for the assessment and monitoring of amyotrophic lateral sclerosis …

M Neumann, O Roesler, J Liscombe, H Kothare… - arXiv preprint arXiv …, 2021 - arxiv.org
We propose a cloud-based multimodal dialog platform for the remote assessment and
monitoring of Amyotrophic Lateral Sclerosis (ALS) at scale. This paper presents our vision …

Spectro-temporal representation of speech for intelligibility assessment of dysarthria

HM Chandrashekar, V Karjigi… - IEEE Journal of Selected …, 2019 - ieeexplore.ieee.org
Recently, spectro-temporal representation of speech has been used in many fields of
speech processing. Owing to this, we explore the use of spectro-temporal representation for …

Speech-based characterization of dopamine replacement therapy in people with Parkinson's disease

R Norel, C Agurto, S Heisig, JJ Rice, H Zhang… - npj Parkinson's …, 2020 - nature.com
People with Parkinson's (PWP) disease are under constant tension with respect to their
dopamine replacement therapy (DRT) regimen. Waiting too long between doses results in …

Bulbar ALS detection based on analysis of voice perturbation and vibrato

M Vashkevich, A Petrovsky… - 2019 Signal Processing …, 2019 - ieeexplore.ieee.org
On average the lack of biological markers causes a one year diagnostic delay to detect
amyotrophic lateral sclerosis (ALS). To improve the diagnostic process an automatic voice …