Sodium channel Nav1. 9 is expressed in peripheral nociceptive neurons, as well as visceral
afferents, and has been shown to act as a threshold channel. Painful peripheral neuropathy …

Only a limited number of animal species lend themselves to becoming model organisms in
multiple biological disciplines: one of these is the great pond snail, Lymnaea stagnalis …

Human pluripotent stem cell–derived cardiomyocytes (hPSC-CMs) are supposed to be a
good human-based model, with virtually unlimited cell source, for studies on mechanisms …

Timing is a crucial aspect of synaptic integration. For pyramidal neurons that integrate
thousands of synaptic inputs spread across hundreds of microns, it is thus a challenge to …

Although species-specific differences in ion channel properties are well-documented, little
has been known about the properties of the human Nav1. 8 channel, an important …

The link between sodium channel Nav1. 7 and pain has been strengthened by identification
of gain-of-function mutations in patients with inherited erythromelalgia (IEM), a genetic …

Behavioral homology is often assumed to involve similarity in underlying neuronal
mechanisms. Here, we provide a counterexample where homologous behaviors are …

Inhibitory autapses are self-innervating synaptic connections in GABAergic interneurons in
the brain. Autapses in neocortical layers have not been systematically investigated, and their …

We show here that hyperpolarization‐activated current (Ih) unexpectedly acts to inhibit the
activity of dorsal root ganglion (DRG) neurons expressing WT Nav1. 7, the largest inward …

The nudibranch mollusc, Dendronotus iris, swims by rhythmically flexing its body from left to
right. We identified a bilaterally represented interneuron, Si3, that provides strong excitatory …