Type 1 diabetes mellitus (T1DM) is a growing global health concern that affects
approximately 8.5 million individuals worldwide. T1DM is characterized by an autoimmune …

Islet transplantation has now become a promising treatment for insulin-deficient diabetes
mellitus. Compared to traditional diabetes treatments, cell therapy can restore endogenous …

Diabetes involves the death or dysfunction of pancreatic β-cells. Analysis of bulk sequencing
from human samples and studies using in vitro and in vivo models suggest that endoplasmic …

Islet transplantation may provide a prospective treatment for type 1 diabetes. To enable islet
transplantation and restore autonomous glucose monitoring and insulin secretion, islets or β …

Stem cell-derived islets (SC-islets) offer the potential to be an unlimited source of cells for
disease modeling and the treatment of diabetes. SC-islets can be genetically modified …

Advancements in diabetes technologies in recent years changed the landscape of type 1
diabetes (T1D) management. 1 Increasing the use of continuous glucose monitors (CGM) …

Type 1 diabetes mellitus (T1DM) is characterized by absolute insulin deficiency primarily
due to autoimmune destruction of pancreatic β‐cells. The prevailing treatment for T1DM …

Diabetes mellitus is a significant global public health challenge, with a rising prevalence and
associated morbidity and mortality. Cell therapy has evolved over time and holds great …

There is a critical need for sorting complex materials, such as pancreatic islets of
Langerhans, exocrine acinar tissues, and embryoid bodies. These materials are cell …

In vitro-generated pluripotent stem cell (PSC)-derived Pax3-induced (iPax3) myogenic
progenitors display an embryonic transcriptional signature, but upon engraftment, the profile …